RAB0719
Human SSSCA1 / Sjoegren Syndrome/Scleroderma Autoantigen 1 ELISA Kit
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About This Item
UNSPSC Code:
41116158
NACRES:
NA.32
Recommended Products
species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
assay range
inter-assay cv: <10%
intra-assay cv: <12%
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... SSSCA1(10534)
General description
The SSSCA1 (Sjoegren syndrome/scleroderma autoantigen 1) gene codes for a cell cycle inhibitor, also called as p27. The SSSCA1 gene is mapped to human chromosome 11q13.1.
The antibody pair provided in this kit recognizes human SSSCA1.
Application
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Biochem/physiol Actions
Sjoegren Syndrome Autoantigen 1 is an important cyclin-dependent kinase complexes inhibitor and prevents the G1 to S phase transition during cell cycle. It is regulated by ubiquitin-proteasome. The Sjoegren Syndrome Autoantigen 1 gene expression is downregulated in cancer and indicates poor prognosis.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Met. Corr. 1
Storage Class Code
8A - Combustible corrosive hazardous materials
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Find documentation for the products that you have recently purchased in the Document Library.
Loss of 3p26. 3 is an independent prognostic factor in patients with oral squamous cell carcinoma.
Uchida K, et al.
Oncology Reports, 26(2), 463-469 (2011)
Subcellular localization of p27 and prostate cancer recurrence: automated digital microscopy analysis of tissue microarrays.
Ananthanarayanan V, et al.
Human Pathology, 42(6), 873-881 (2011)
Expression of CRM1 in human gliomas and its significance in p27 expression and clinical prognosis.
Shen A, et al.
Neurosurgery, 65(1), 153-160 (2009)
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