N2165

NKY80

≥98% (HPLC)

• Synonym(s): 2-Amino-7-(2-furanyl)-7,8-dihydro-5(6H)-quinazolinone
• Empirical Formula (Hill Notation): C₁₂H₁₁N₃O₂
• CAS Number: 299442-43-6
• Molecular Weight: 229.23
• MDL number: MFCD02026323
• UNSPSC Code: 41106305
• PubChem Substance ID: 329818599
• NACRES: NA.77

Properties

• Assay: ≥98% (HPLC)
• form: powder
• color: off-white to light brown
• solubility: DMSO: ≥30 mg/mL
• storage temp.: 2-8°C
• SMILES string: Nc1ncc2C(=O)CC(Cc2n1)c3ccco3
• InChI: 1S/C12H11N3O2/c13-12-14-6-8-9(15-12)4-7(5-10(8)16)11-2-1-3-17-11/h1-3,6-7H,4-5H2,(H2,13,14,15)
• InChI key: SOJUSNIBPPMLCC-UHFFFAOYSA-N

Description

Biochem/physiol Actions

NKY80 is a selective adenylyl cyclase-V inhibitor with greater than 200-fold selectivity for type V over the type II isoform.

Features and Benefits

This compound is a featured product for ADME Tox and Cyclic Nucleotide research. Discover more featured ADME Tox and Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Adenylyl cyclases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302
• Precautionary Statements: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable