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H6635

Sigma-Aldrich

Hydrocortisone 3-(O-carboxymethyl)oxime

Synonym(s):

11β,17α,21-Trihydroxy-4-pregnene-3,20-dione 3-(O-carboxymethyl)oxime, 4-Pregnene-11β,17α,21-triol-3,20-dione 3-(O-carboxymethyl)oxime, Cortisol 3-(O-carboxymethyl)oxime

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About This Item

Empirical Formula (Hill Notation):
C23H33NO7
CAS Number:
Molecular Weight:
435.51
MDL number:
UNSPSC Code:
12352202
PubChem Substance ID:
NACRES:
NA.77

biological source

synthetic (organic)

Assay

≥85% (HPLC)

form

powder

solubility

chloroform: methanol (1:1): 20 mg/mL, clear, colorless to light yellow

shipped in

ambient

storage temp.

room temp

SMILES string

[H][C@@]12CCC3=CC(\CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]4(C)[C@@]2([H])CC[C@]4(O)C(=O)CO)=N\OCC(O)=O

InChI

1S/C23H33NO7/c1-21-7-5-14(24-31-12-19(28)29)9-13(21)3-4-15-16-6-8-23(30,18(27)11-25)22(16,2)10-17(26)20(15)21/h9,15-17,20,25-26,30H,3-8,10-12H2,1-2H3,(H,28,29)/b24-14+/t15-,16-,17-,20+,21-,22-,23-/m0/s1

InChI key

WXAWNCDYPXVODT-ZAKIEOBNSA-N

Application

Hydrocortisone 3-(O-carboxymethyl)oxime has been used in fecal steroid hormone processing and analysis.

Biochem/physiol Actions

Hydrocortisone 3-(O-carboxymethyl)oxime is used as the analog of cortisol. It is used to modify the surface of an Au chip.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Development of indirect competitive immuno-assay method using SPR detection for rapid and highly sensitive measurement of salivary cortisol levels
Tahara Y, et al.
Frontiers in Bioengineering and Biotechnology, 2, 15-15 (2014)
Characterization of ovarian steroid patterns in female African lions (Panthera leo), and the effects of contraception on reproductive function
Putman S B, et al.
PLoS ONE, 10(10), e0140373-e0140373 (2015)

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