Skip to Content
Merck
All Photos(1)

Documents

G1013

Sigma-Aldrich

Gly-Arg 4-methoxy-β-naphthylamide dihydrochloride

dipeptidyl aminopeptidase I substrate

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C19H26N6O3 · 2HCl
CAS Number:
Molecular Weight:
459.37
MDL number:
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.32

Quality Level

Assay

≥99% (TLC)

form

powder

solubility

ethanol: 20 mg/mL, clear, colorless to yellow

storage temp.

2-8°C

SMILES string

Cl.COc1cc(NC(=O)C(CCCNC(N)=N)NC(=O)CN)cc2ccccc12

InChI

1S/C19H26N6O3.ClH/c1-28-16-10-13(9-12-5-2-3-6-14(12)16)24-18(27)15(25-17(26)11-20)7-4-8-23-19(21)22;/h2-3,5-6,9-10,15H,4,7-8,11,20H2,1H3,(H,24,27)(H,25,26)(H4,21,22,23);1H

InChI key

ZMJQLLSJSFQLTM-UHFFFAOYSA-N

Application

Gly-Arg 4-methoxy-β-naphthylamide dihydrochloride has been used as a substrate to measure the dipeptidyl peptidase I (DPPI) activity in human leukemia cell line.

Substrates

Substrate for dipeptidyl aminopeptidase I

Pictograms

Health hazard

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Carc. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

M J McGuire et al.
Archives of biochemistry and biophysics, 295(2), 280-288 (1992-06-01)
The lysosomal hydrolase, dipeptidyl peptidase I (DPPI), was purified from human spleen and its enzymatic activity characterized. The enzyme was purified to apparent homogeneity by a combination of differential pH solubility, heat-treatment, affinity chromatography on concanavalin A-agarose and p-hydroxymercuribenzoate-agarose, and

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service