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F3272

Sigma-Aldrich

Inulin–FITC

from dahlia tuber

Synonym(s):

Fluorescein isothiocyanate–inulin

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1 G
$1,390.00

$1,390.00


Estimated to ship on17 April 2025


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1 G
$1,390.00

About This Item

MDL number:
UNSPSC Code:
12352201
NACRES:
NA.25

$1,390.00


Estimated to ship on17 April 2025


Request a Bulk Order

biological source

dahlia tuber

Quality Level

form

powder

mol wt

2,000-5,000

color

light yellow to dark yellow, to dark orange

solubility

water: soluble, clear

storage temp.

2-8°C

Application


  • Development and validation of bioengineered intestinal tubules for translational research aimed at safety and efficacy testing of drugs and nutrients.: This study employs Inulin–FITC to investigate the absorption characteristics of bioengineered intestinal models, providing critical data on gut permeability and nutrient interaction, which is crucial for pharmaceutical and nutritional research (Jochems et al., 2019).

  • Role of Vitamin D in Maintaining Renal Epithelial Barrier Function in Uremic Conditions.: Utilizes Inulin–FITC to measure the efficacy of Vitamin D in preserving renal barrier function under stress conditions, which could lead to new treatments for chronic kidney disease (Mihajlovic et al., 2017).

  • Inhibition of p38 mitogen-activated protein kinase attenuates butyrate-induced intestinal barrier impairment in a Caco-2 cell monolayer model.: This investigation highlights the role of Inulin–FITC in studying the protective effects of kinase inhibition on intestinal barriers, relevant for gastrointestinal disorder treatments (Huang et al., 2014).

  • Measurement of glomerular filtration rate in conscious mice using FITC-inulin clearance.: Demonstrates the utility of Inulin–FITC in precise, non-invasive measurements of renal function, essential for nephrology research and therapy development (Qi and Breyer, 2009).

  • PPAR gamma agonist normalizes glomerular filtration rate, tissue levels of homocysteine, and attenuates endothelial-myocyte uncoupling in alloxan induced diabetic mice.: Incorporates Inulin–FITC to assess the efficacy of a PPAR gamma agonist in diabetic nephropathy, providing insights into metabolic disease management (Rodriguez et al., 2008).

Other Notes

To gain a comprehensive understanding of our extensive range of Oligosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Richard B van Breemen et al.
Expert opinion on drug metabolism & toxicology, 1(2), 175-185 (2006-08-23)
Caco-2 cells are a human colon epithelial cancer cell line used as a model of human intestinal absorption of drugs and other compounds. When cultured as a monolayer, Caco-2 cells differentiate to form tight junctions between cells to serve as
Nicholas Ferrell et al.
Biotechnology and bioengineering, 107(4), 707-716 (2010-06-17)
We have developed a bilayer microfluidic system with integrated transepithelial electrical resistance (TEER) measurement electrodes to evaluate kidney epithelial cells under physiologically relevant fluid flow conditions. The bioreactor consists of apical and basolateral fluidic chambers connected via a transparent microporous
Grant Backer et al.
Physiological genomics, 50(8), 543-552 (2018-04-14)
Mesangial matrix expansion is an important process in the initiation of chronic kidney disease, yet the genetic factors driving its development are unknown. Our previous studies have implicated Far2 as a candidate gene associated with differences in mesangial matrix expansion
Jun Sugama et al.
Diabetes, obesity & metabolism, 23(1), 86-96 (2020-09-08)
To examine the effects of an enteropeptidase inhibitor, SCO-792, on kidney function in rats. The pharmacological effects of SCO-792 were evaluated in Wistar fatty (WF) rats, a rat model of diabetic kidney disease (DKD). Oral administration of SCO-792 increased faecal
N T Baker et al.
Microbial pathogenesis, 49(5), 260-272 (2010-07-06)
Campylobacter fetus is a recognized pathogen of cattle and sheep, though human infection has also been reported. Ingestion of contaminated food or water is a proposed route of transmission for both humans and animals. The subsequent detection of the organism

Articles

Explore FITC-labelled polysaccharides and their properties, including impact of molecular weight on molecule dimensions.

Questions

  1. Where can I find the information on making a solution for Inulin–FITC?

    1 answer
    1. The solvent used is water. FITC-Inulin has a challenging solubility due to the slow formation of an aggregate when solutions of Inulin (and Inulin derivatives) are allowed to cool to room temperature, resulting in a cloudy solution. It is recommended to heat the samples to 80 degrees until the solution is completely clear, as this will ensure that it remains clear for more than 24 hours. Freezing the sample would result in a cloudy solution again.

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