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E7263

Sigma-Aldrich

Ethynodiol diacetate

Synonym(s):

(3β, 17α)-19-Norpregn-4-en-20-yne-3,17-diol diacetate, 3β,17β-Diacetoxy-17α-ethynyl-4-estrene, Etynodiol acetate

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About This Item

Empirical Formula (Hill Notation):
C24H32O4
CAS Number:
297-76-7
Molecular Weight:
384.51
EC Number:
206-044-9
MDL number:
MFCD00083326
UNSPSC Code:
41116107
PubChem Substance ID:
24894643
NACRES:
NA.77

SMILES string

[H][C@]12CC[C@H](OC(C)=O)C=C1CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@@]4(OC(C)=O)C#C

InChI

1S/C24H32O4/c1-5-24(28-16(3)26)13-11-22-21-8-6-17-14-18(27-15(2)25)7-9-19(17)20(21)10-12-23(22,24)4/h1,14,18-22H,6-13H2,2-4H3/t18-,19-,20+,21+,22-,23-,24-/m0/s1

InChI key

ONKUMRGIYFNPJW-KIEAKMPYSA-N

Gene Information

human ... PGR(5241)

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Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Warning

Hazard Statements

H302 + H312 + H332,H351

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Contraceptive failure and the progestogen-only pill.
Louise Melvin
The journal of family planning and reproductive health care, 36(3), 182-182 (2010-07-28)
A E Czeizel et al.
Contraception, 51(1), 19-24 (1995-01-01)
A case-control study on different groups of isolated congenital limb deficiency was performed in a ten-year population-based and revised Hungarian data set. A higher rate of one contraceptive pill type with relatively high dose (ethynodiol diacetate 1.0 mg + ethinyloestradiol
G A Hill et al.
The Journal of reproductive medicine, 36(4 Suppl), 334-339 (1991-04-01)
A phase IV, open-label, multicenter survey of 983 obstetrician-gynecologists was conducted to evaluate the incidence of intermenstrual bleeding in 6,382 women receiving a low-dose monophasic oral contraceptive, ethynodiol diacetate, 1 mg, with ethinyl estradiol, 35 micrograms (EDA 1 mg with
Serum valproate levels with oral contraceptive use.
Andrew G Herzog et al.
Epilepsia, 46(6), 970-971 (2005-06-11)
Marta Coromina Sadurni et al.
Psychiatry research, 170(2-3), 290-291 (2009-10-20)
Premenstrual psychosis is a rare and not formally recognized disorder (DSM-IVR, ICD-10). The literature mainly consists of clinical cases. There have been preliminary reports of improvement in such cases after administration of oral contraceptives. We present a case of premenstrual
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