S9876

Sulfathiazole

• Synonym(s): 2-Sulfanilamidothiazole, 4-Amino-N-(2-thiazolyl)benzenesulfonamide, N₁-(2-Thiazolyl)sulfanilamide
• Empirical Formula (Hill Notation): C₉H₉N₃O₂S₂
• CAS Number: 72-14-0
• Molecular Weight: 255.32
• Beilstein: 226178
• EC Number: 200-771-5
• MDL number: MFCD00005319
• UNSPSC Code: 41116107
• PubChem Substance ID: 329824636
• NACRES: NA.24

Properties

• grade: analytical standard
• Quality Level: 100
• Agency: EPA 1694
• form: powder
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• mp: 200-202 °C (lit.)
• application(s): clinical testing
• SMILES string: Nc1ccc(cc1)S(=O)(=O)Nc2nccs2
• InChI: 1S/C9H9N3O2S2/c10-7-1-3-8(4-2-7)16(13,14)12-9-11-5-6-15-9/h1-6H,10H2,(H,11,12)
• InChI key: JNMRHUJNCSQMMB-UHFFFAOYSA-N

Description

General description

Sulfathiazole is a broad-spectrum antibacterial drug, belonging to the class of sulfonamides, used in veterinary and human medication for the treatment of infections. It is also involved in promoting growth of livestock and fish.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Sulfathiazole is used as an analytical reference standard for the quantification of the analyte in meat, and honey samples using different chromatography techniques.

Biochem/physiol Actions

Sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase.
Mode of Action: Inhibits folic acid synthesis in prokaryotes.
Anti-microbial Spectrum: Gram positive, Gram negative, Chlamydia
Mode of Resistance: Alteration of dihydropteroate synthase or alternative pathway for folic acid synthesis.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335,H412
• Precautionary Statements: P261 - P264 - P271 - P273 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Aquatic Chronic 3 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves