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H5144

Supelco

Heroin hydrochloride solution

100 μg/mL in methanol, analytical standard, for drug analysis

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About This Item

Empirical Formula (Hill Notation):
C21H23NO5 · HCl
CAS Number:
1502-95-0
Molecular Weight:
405.87
EC Number:
200-659-6
MDL number:
MFCD00190605
UNSPSC Code:
41116107
PubChem Substance ID:
329815214
NACRES:
NA.24

grade

analytical standard, for drug analysis

Quality Level

200

drug control

Home Office Schedule 2; stupéfiant (France); kontrollierte Droge in Deutschland; (Spain); Decreto Lei 15/93: Tabela IA (Portugal)

concentration

100 μg/mL in methanol (± 5%)
100 μg/mL in methanol

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

single component solution

storage temp.

−20°C

SMILES string

Cl.CN1CC[C@]23[C@H]4Oc5c(OC(C)=O)ccc(C[C@@H]1[C@@H]2C=C[C@@H]4OC(C)=O)c35

InChI

1S/C21H23NO5.ClH/c1-11(23)25-16-6-4-13-10-15-14-5-7-17(26-12(2)24)20-21(14,8-9-22(15)3)18(13)19(16)27-20;/h4-7,14-15,17,20H,8-10H2,1-3H3;1H/t14-,15+,17-,20-,21-;/m0./s1

InChI key

FZJYQGFGNHGSFX-PVQKIFDLSA-N

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Application

Heroin hydrochloride solution may be used as a reference standard for the analysis of heroin in plasma samples using high-performance liquid chromatography (HPLC) technique.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

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Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

51.8 °F - closed cup

Flash Point(C)

11 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
SLBW7395
SLBS7193
SLBR6044V
SLBH6517V
050M8705V

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The quantitative analysis of heroin, methadone and their metabolites and the simultaneous detection of cocaine, acetylcodeine and their metabolites in human plasma by high-performance liquid chromatography coupled with tandem mass spectrometry.
Rook.JE, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 824(1-2), 213-221 (2005)
Ruixue Yin et al.
International journal of medical sciences, 10(3), 299-306 (2013-02-21)
To investigate whether microvascular damage is involved in the pathogenesis of heroin induced spongiform leukoencephalopathy (HSLE). The brain tissues were collected from 4 HSLE patients and 5 controls and then fixed in 4% paraformaldehyde. The frontal lobe, corpus callosum and
Marc Walter et al.
Journal of clinical psychopharmacology, 33(2), 193-198 (2013-02-21)
Heroin dependence is associated with a stressful environment and with dysfunction of the hypothalamic-pituitary-adrenal (HPA) axis. The present study examined the acute effects of intravenous heroin versus placebo on the HPA axis response in heroin-dependent patients. Twenty-eight heroin-dependent patients in
Hannah Skuse et al.
Emergency nurse : the journal of the RCN Accident and Emergency Nursing Association, 20(9), 14-19 (2013-03-23)
This article discusses the administration of intranasal diamorphine as an analgesia-in paediatric trauma care. The authors outline evidence for its use and discuss a recent multicentre safety study of an intranasal diamorphine product. In addition, they advise emergency department nurses
D Adam Algren et al.
Journal of medical toxicology : official journal of the American College of Medical Toxicology, 9(1), 106-115 (2013-01-30)
During the summer of 2005, multiple cities in the United States began to report outbreaks of fentanyl-associated fatalities among illicit drug users. The objectives of this study were to (1) determine if an outbreak of fentanyl-associated fatalities occurred in mid-2005
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