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G6895

Supelco

Glafenine

analytical standard

Synonym(s):

1-Glyceryl N-(7-chloro-4-quinolyl)anthranilate

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About This Item

Empirical Formula (Hill Notation):
C19H17ClN2O4
CAS Number:
3820-67-5
Molecular Weight:
372.80
EC Number:
223-315-7
MDL number:
MFCD00079326
UNSPSC Code:
41116107
PubChem Substance ID:
329799956

grade

analytical standard

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

OCC(O)COC(=O)c1ccccc1Nc2ccnc3cc(Cl)ccc23

InChI

1S/C19H17ClN2O4/c20-12-5-6-14-17(7-8-21-18(14)9-12)22-16-4-2-1-3-15(16)19(25)26-11-13(24)10-23/h1-9,13,23-24H,10-11H2,(H,21,22)

InChI key

GWOFUCIGLDBNKM-UHFFFAOYSA-N

Gene Information

human ... PTGS1(5742) , PTGS2(5743)

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
018F0671

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C Moesch et al.
European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies, 31(5), 329-333 (1993-05-01)
Glaphenine is an analgesic drug derived from anthranilic acid. We report the analytical procedures for stone analysis in three cases of common bile duct stones containing glaphenic acid, which developed in arthrosic patients treated for 13.7 +/- 5 years with
Bo Wen et al.
Drug metabolism and disposition: the biological fate of chemicals, 39(9), 1511-1521 (2011-06-02)
Glafenine (Privadol; 2,3-dihydroxypropyl 2-[(7-chloro-4-quinolinyl) amino]benzoate) is a non-narcotic analgesic agent widely used for the treatment of pains of various origins. Severe liver toxicity and a high incidence of anaphylaxis were reported in patients treated with glafenine, eventually leading to its
Renaud Robert et al.
Molecular pharmacology, 77(6), 922-930 (2010-03-05)
Cystic fibrosis (CF) is caused by mutations in the CF transmembrane conductance regulator (CFTR) gene, which encodes a cAMP-activated anion channel expressed in epithelial cells. The most common mutation Delta Phe508 leads to protein misfolding, retention by the endoplasmic reticulum
Claudia Müller et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 773(1), 47-52 (2002-05-17)
Ion suppression effects during electrospray-ionsation mass spectrometry (ESI-MS) caused by different sample preparation procedures for serum were investigated. This topic is of importance for systematic toxicological analysis for which LC-ESI-MS has been developed with transport-region collision-induced dissociation (ECI-CID) and mass
B H Stricker et al.
European journal of clinical pharmacology, 40(4), 367-371 (1991-01-01)
In 1981 generalized anaphylaxis was registered on 166 occasions in Dutch general and academic hospitals. Clinical details of 120 of those patients revealed that in 107 anaphylaxis was either probable (n = 90) or possible (n = 17), whereas in
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