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Key Documents

85549

Sigma-Aldrich

Span® 85

Synonym(s):

Sorbitan trioleate, Span® 85

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About This Item

Empirical Formula (Hill Notation):
C60H108O8
CAS Number:
Molecular Weight:
957.49
EC Number:
MDL number:
UNSPSC Code:
12161900
PubChem Substance ID:

description

non-ionic

refractive index

n20/D 1.476 (lit.)

viscosity

200-300 mPa.s(20 °C)

HLB value

1.8±1.1

density

0.94 g/mL at 20 °C
0.956 g/mL at 25 °C (lit.)

SMILES string

CCCCCCCC\C=C/CCCCCCCC(=O)O[C@H](CO)[C@H]1OC[C@H](OC(=O)CCCCCCC\C=C/CCCCCCCC)[C@H]1OC(=O)CCCCCCC\C=C/CCCCCCCC

InChI

1S/C60H108O8/c1-4-7-10-13-16-19-22-25-28-31-34-37-40-43-46-49-56(62)65-52-54(61)59-60(68-58(64)51-48-45-42-39-36-33-30-27-24-21-18-15-12-9-6-3)55(53-66-59)67-57(63)50-47-44-41-38-35-32-29-26-23-20-17-14-11-8-5-2/h25-30,54-55,59-61H,4-24,31-53H2,1-3H3/b28-25-,29-26-,30-27+/t54-,55+,59-,60-/m1/s1

InChI key

ZBNRGEMZNWHCGA-WECPCUOASA-N

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Legal Information

Span is a registered trademark of Croda International PLC

replaced by

Product No.
Description
Pricing

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

437.0 °F

Flash Point(C)

225 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Gülay Büyükköroğlu et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 109, 174-183 (2016-10-30)
Cervical cancer is one of the most life threatening types of cancer among women and is generally resistant to chemotherapy. The objective of this study was to prepare a vaginal suppository containing a chemotherapeutic agent and a genetic material that
Ming-Hsi Huang et al.
PloS one, 5(8), e12279-e12279 (2010-09-03)
Antigen sparing and cross-protective immunity are regarded as crucial in pandemic influenza vaccine development. Both targets can be achieved by adjuvantation strategy to elicit a robust and broadened immune response. We assessed the immunogenicity of an inactivated H5N1 whole-virion vaccine
P M Blackett et al.
Pharmaceutical research, 12(11), 1689-1693 (1995-11-01)
The purpose of the work is to study the adsorption of Oleic acid and Span 85 (materials frequently used in aerosols as surfactants) onto partially amorphous and essentially crystalline salbutamol sulphate, attempting to understand the behaviour of metered dose inhalers
Hiroaki Todo et al.
International journal of pharmaceutics, 271(1-2), 41-52 (2004-05-08)
The effect of pulmonary absorption enhancers on the stability of active ingredients is an important factor for successful inhalation therapy as well as the effect on pharmacological activity and safety. We examined the effect of pulmonary absorption enhancers on the
A N Hassan et al.
International journal of food microbiology, 87(1-2), 145-152 (2003-08-21)
The influence of surfactant hydrophobicity on detachment of Escherichia coli O157:H7 from lettuce was determined. Lettuce pieces inoculated with the pathogen were rinsed with Tween and Span surfactants of different hydrophobicity. Of the Tweens, only Tween 85, the Tween with

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