33871
2-Nitrobenzaldehyde semicarbazone
VETRANAL®, analytical standard
Synonym(s):
2-NP-SCA, 4-(2-Nitrobenzylidene)semicarbazide
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About This Item
Empirical Formula (Hill Notation):
C8H8N4O3
CAS Number:
Molecular Weight:
208.17
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
Recommended Products
grade
analytical standard
Quality Level
product line
VETRANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
clinical testing
format
neat
SMILES string
NC(=O)N\N=C\c1ccccc1[N+]([O-])=O
InChI
1S/C8H8N4O3/c9-8(13)11-10-5-6-3-1-2-4-7(6)12(14)15/h1-5H,(H3,9,11,13)/b10-5+
InChI key
OEOKLBSECDAYSM-BJMVGYQFSA-N
General description
2-Nitrobenzaldehyde semicarbazone is a semicarbazone derivative of 2-Nitrobenzaldehyde.
Application
2-Nitrobenzaldehyde semicarbazone (2-NBA-SC) may be used as an analytical reference standard for the determination of 2-NBA-SC in:
- Animal muscle tissues by solid-phase extraction (SPE) and high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) equipped with electrospray ionization (ESI) source and multiple reaction monitoring (MRM) detection.
- Milk of dairy cows by LC-MS/MS with selected reaction monitoring (SRM) detection.
- Azodicarbonamide-treated flour samples by isotope dilution liquid chromatography coupled to ESI-LC-MS/MS.
- Shrimp dosed with nitrofurans by ESI-LC-MS/MS with SRM detection.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Other Notes
Derivatized standard for the assay of nitrofurans in animal tissue by LC/MS
Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Journal of agricultural and food chemistry, 52(18), 5730-5734 (2004-09-18)
Semicarbazide was previously found in foods that were in contact with rubber gaskets foamed at high temperatures with a blowing agent azodicarbonamide. Because azodicarbonamide is an approved flour additive in certain countries, we set out to ascertain if semicarbazide is
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