ABN363

Anti-Myelin Protein P0 Antibody

from rabbit, purified by affinity chromatography

• Synonym(s): Myelin protein P0, Myelin peripheral protein, MPP, Myelin protein zero
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• purified by: affinity chromatography
• species reactivity: rat, mouse
• species reactivity (predicted by homology): bovine (based on 100% sequence homology), horse (based on 100% sequence homology), human (based on 100% sequence homology)
• technique(s): immunohistochemistry: suitable (paraffin); western blot: suitable
• NCBI accession no.: NP_000521
• UniProt accession no.: P25189
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... MPZ(4359)

Description

General description

Myelin protein P0 is also called Myelin peripheral protein (MPP) and Myelin protein zero (MPZ). Myelin protein P0 is found only in peripheral nervous system and is involved in the creation of an extracellular membrane face which guides the wrapping process that eventually leads to the compaction of adjacent lamellae. Myelin protein P0 is related to several disease states including Charcot-Marie-Tooth disease 1B (CMT1B), Charcot-Marie-Tooth disease 2I (CMT2I), Charcot-Marie-Tooth disease 2J (CMT2J), Adie pupil (ADIEP), Charcot-Marie-Tooth disease, dominant, intermediate type, D (CMTDID), Dejerine-Sottas syndrome (DSS), Congenital hypomyelination neuropathy (CHN), and Roussy-Levy syndrome (ROULS).

Immunogen

KLH-conjugated linear peptide corresponding to the extracellular domain of human Myelin protein P0.

Application

Anti-Myelin Protein P0 Antibody is a highly specific rabbit polyclonal antibody, that targets Myelin Protein & has been tested in western blotting & IHC (Paraffin).

Immunohistochemistry Analysis: A 1:2,000 dilution of this antibody detected Myelin protein P0 in rat spinal cord sections.

Research Category
Neuroscience

Research Sub Category
Developmental Neuroscience

Quality

Evaluated by Western Blotting in rat spinal cord tissue lysate.

Western Blotting Analysis: A 1:5,000 dilution of this antibody detected Myelin protein P0 in 10 µg of rat spinal cord tissue lysate.

Target description

~30 kDa observed

Physical form

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable