Skip to Content
Merck
All Photos(2)

Key Documents

View All Documentation

1.12635

SAFC

Parteck® Delta M (Mannitol)

EMPROVE® ESSENTIAL, Ph. Eur., BP, ChP, JP, USP, E 421

Pharma Manufacturing

Synonym(s):

D-Mannitol

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Empirical Formula (Hill Notation):
C6H14O6
CAS Number:
69-65-8
Molecular Weight:
182.17
MDL number:
MFCD00064287
UNSPSC Code:
12352201
E Number:
E421
EC Index Number:
200-711-8
Pricing and availability is not currently available.

Agency

BP
ChP
JP
Ph. Eur.
USP

Quality Level

500

description

EMPROVE® ESSENTIAL Ph Eur,BP,USP,JP,E 421

product line

EMPROVE® ESSENTIAL

form

fine powder

autoignition temp.

410 °C

potency

13500 mg/kg LD50, oral (Rat)

pH

5-7 (20 °C, 100 g/L in H2O)

bp

290-295 °C/4 hPa

mp

164-169 °C

application(s)

liquid formulation
pharmaceutical
solid formulation

storage temp.

2-25°C

InChI

1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2

InChI key

FBPFZTCFMRRESA-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

With formulation challenges in mind, we have used particle engineering technologies to develop functional excipients specifically for solid dosage forms. The products in our Parteck® portfolio feature unique particle properties tailored for excellent performance in tableting processes, for specific drug delivery technologies, or for solubility enhancement.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Parteck® Delta M excipient is a convertible mannitol specifically designed to handle wet granulation. Its delta-polymorphic crystals make it extremely adaptable. While it is monographed as a standard mannitol, this exceptional excipient changes its structure and converts into a beta-polymorph when it comes into contact with water. This creates a porous structure, thereby increasing the surface area, which leads to the ability to produce exceptionally hard tablets with fast disintegration.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
PARTECK is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

What is the Emprove® Program?

The Emprove® Program is a system providing comprehensive and thorough documentation of our filters and single-use components, pharma raw materials, and starting materials. Four document types are included with an Emprove® Program subscription:

Material Qualification Dossier

Free of charge - Sign in to download

Quality Management Dossier (Open Access)

Free of charge - Sign in to download

Operational Excellence Dossier

Available by subscription or for a fee

Learn more about the benefits an Emprove® Program subscription can provide
Why are these documents unavailable?
Emprove® Dossiers contain information intended to support the registration process and risk assessment activities of pharmaceutical producers and contain confidential information. Please contact us if you would like access.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service