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Merck

1.08510

SAFC

Vanillin

EMPROVE® ESSENTIAL, Ph. Eur., BP, NF

Pharma Manufacturing

Synonym(s):

Vanillin, 4-Hydroxy-3-methoxybenzaldehyde

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About This Item

Linear Formula:
(CH3O)(OH)C6H3CHO
CAS Number:
Molecular Weight:
152.15
MDL number:
UNSPSC Code:
12352114
EC Index Number:
204-465-2
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Agency

BP
NF
Ph. Eur.

Quality Level

vapor pressure

0.0029 hPa ( 25 °C)

product line

EMPROVE® ESSENTIAL

form

solid

autoignition temp.

>400 °C

technique(s)

API processing | cocrystal formation: suitable

pH

4.3 (20 °C, 10 g/L in H2O)

mp

80-83.5 °C

transition temp

flash point 160 °C

solubility

9 g/L

density

1.06 g/cm3 at 20 °C

application(s)

liquid formulation
pharmaceutical
solid formulation

storage temp.

15-25°C

InChI

1S/C8H8O3/c1-11-8-4-6(5-9)2-3-7(8)10/h2-5,10H,1H3

InChI key

MWOOGOJBHIARFG-UHFFFAOYSA-N

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General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our EMPROVE® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Vanillin is a commonly used ingredient in food and pharmaceutics. In pharmaceutical applications, vanillin has been used primarily as flavor enhancer for oral dosage forms.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

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Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

319.6 - 321.4 °F - closed cup

Flash Point(C)

159.8 - 160.8 °C - closed cup


What is the Emprove® Program?

The Emprove® Program is a system providing comprehensive and thorough documentation of our filters and single-use components, pharma raw materials, and starting materials. Four document types are included with an Emprove® Program subscription:

Material Qualification Dossier

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Quality Management Dossier (Open Access)

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Operational Excellence Dossier

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Why are these documents unavailable?
Emprove® Dossiers contain information intended to support the registration process and risk assessment activities of pharmaceutical producers and contain confidential information. Please contact us if you would like access.

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