860524P

C24 Ceramide (d18:1/24:0)

Avanti Research^™ - A Croda Brand

• Synonym(s): N-lignoceroyl-D-erythro-sphingosine
• Empirical Formula (Hill Notation): C₄₂H₈₃NO₃
• CAS Number: 102917-80-6
• Molecular Weight: 650.11
• MDL number: MFCD02259276
• UNSPSC Code: 12352211
• NACRES: NA.25

Properties

• form: powder
• packaging: pkg of 1 × 10 mg (860524P-10mg); pkg of 1 × 5 mg (860524P-5mg); pkg of 1 × 50 mg (860524P-50mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand
• lipid type: sphingolipids
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: OC[C@]([H])(NC(CCCCCCCCCCCCCCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC
• InChI: 1S/C42H83NO3/c1-3-5-7-9-11-13-15-17-18-19-20-21-22-23-24-26-28-30-32-34-36-38-42(46)43-40(39-44)41(45)37-35-33-31-29-27-25-16-14-12-10-8-6-4-2/h35,37,40-41,44-45H,3-34,36,38-39H2,1-2H3,(H,43,46)/b37-35+/t40-,41+/m0/s1
• InChI key: ZJVVOYPTFQEGPH-AUTSUKAISA-N

Description

General description

C24 Ceramide has long acyl chain length of 24 carbon units.[1]

Application

C24 Ceramide (d18:1/24:0) has been used:

• in the generation of small unilamellar vesicles[2]
• as an internal standard in liquid chromatography-mass spectrometry for ceramide quantification from rat samples[3]
• to test its effect on mitochondrial stress response in worms[4]

Biochem/physiol Actions

C24 ceramide induces mitochondrial stress response.[3] Its levels are depleted in coronary artery disease (CAD).[5] However, elevated ceramide levels is observed in Alzheimer′s disease.[6] C24 is synthesized during stress. It mediates spontaneous neutrophil death.[7]

Packaging

5 mL Amber Glass Screw Cap Vial (860524P-10mg)

5 mL Amber Glass Screw Cap Vial (860524P-50mg)

5 mL Amber Glass Screw Cap Vial (860524P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids