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860357P

Avanti

16:0 PC-d71

Avanti Research™ - A Croda Brand, powder

Synonym(s):

1,2-Dipalmitoyl-d62-sn-glycero-3-phosphocholine-N,N,N-trimethyl-d9

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About This Item

Empirical Formula (Hill Notation):
C40H9NO8PD71
CAS Number:
474943-49-2
Molecular Weight:
805.48
UNSPSC Code:
12352100
NACRES:
NA.25

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (860357P-10MG)

manufacturer/tradename

Avanti Research™ - A Croda Brand

technique(s)

mass spectrometry (MS): suitable

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCC[N+](C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])=O)(OC(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2

General description

Phosphatidylcholine (PC) (Lecithins) is a zwitterion with a quaternary ammonium group and a phosphate moiety in its structure. PC generally possesses saturated fatty acid in the sn-1 position and unsaturated fatty acid at sn-2 position. PC is a strong bilayer forming lipid, present abundantly in mammalian membranes. cytidine diphosphate-choline (CDP-choline) is the precursor for PC synthesis. Selective deuteration of this lipid may have applications in structural studies using techniques such as nuclear magnetic resonance (NMR), neutron reflectivity and small-angle neutron scattering.

Biochem/physiol Actions

Phosphatidylcholine (PC) plays a key role in cholesterol transport and membrane lipid homeostasis. It is the precursor for sphingomyelin synthesis. PC is essential for the synthesis of signaling molecules like diacyl glycerol (DAG), phosphatidic acid and lysophosphatidic acid. 16:0 PC (DPPC) is the key phospholipid in the lipid bilayer of the membranes and also major constituent of lung surfactant.

Packaging

5 mL Amber Glass Screw Cap Vial (860357P-10MG)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Isotherms of dipalmitoylphosphatidylcholine (DPPC) monolayers: features revealed and features obscured
Klopfer KJ and Vanderlick TK
Journal of Colloid and Interface Science, 182(1), 220-229 (1996)
Essentials of Medical Biochemistry (2011)
Biosynthetic preparation of selectively deuterated phosphatidylcholine in genetically modified Escherichia coli
Maric S, et al.
Applied Microbiology and Biotechnology, 99(1), 241-254 (2015)
The Membranes of Cells (2016)
Phosphatidylcholine: greasing the cholesterol transport machinery
Lagace TA
Lipid insights, 8, LPI-S31746 (2015)
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