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B65705

Sigma-Aldrich

2-Bromoethylamine hydrobromide

99%

Synonym(s):

2-Aminoethyl bromide hydrobromide

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About This Item

Linear Formula:
BrCH2CH2NH2 · HBr
CAS Number:
2576-47-8
Molecular Weight:
204.89
Beilstein:
3607605
EC Number:
219-924-2
MDL number:
MFCD00012886
UNSPSC Code:
12352100
PubChem Substance ID:
24891920
NACRES:
NA.22

Assay

99%

form

crystals

mp

170-175 °C (lit.)

SMILES string

Br.NCCBr

InChI

1S/C2H6BrN.BrH/c3-1-2-4;/h1-2,4H2;1H

InChI key

WJAXXWSZNSFVNG-UHFFFAOYSA-N

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Application

2-Bromoethylamine hydrobromide can be used as a reactant to synthesize:
  • Thiazolines and thiazines via tandem S-alkylation-cyclodeamination of thioamides/haloamines.
  • Optically active tertiary phosphines via cesium hydroxide-catalyzed P-alkylation of secondary phosphines.
  • Secondary amines via CsOH-promoted chemoselective mono-N-alkylation of primary amines, diamines, and polyamines.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302,H412

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

142.9 °F - Pensky-Martens closed cup

Flash Point(C)

61.6 °C - Pensky-Martens closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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To aid in evaluating the performance of biomarkers, we measured kidney injury biomarkers in rat models of drug-induced acute kidney injury. Rats were treated with site-specific nephrotoxins, puromycin, gentamicin, cisplatin, or 2-bromoethylamine. Fifteen biomarkers (β-2-microglobulin, calbindin, clusterin, cystatin-C, KIM-1, GST-α
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