Chemical & pharmaceutical bulletin, 45(4), 668-674 (1997-04-01)
Two new series of 2-arylmethyl-1,4-benzoquinones (2 and 3) were synthesized for evaluation of their pharmacological activities. These compounds showed significant inhibition of platelet aggregation and some of them possessed a protective against endothelial cell injury. Structure-activity relationship studies indicated that
Heterogeneously Pd/C catalysed procedure for the vinylation of aryl bromides.
Joucla L, et al.
Applied Catalysis A: General, 360(2), 145-153 (2009)
Concurrent inhibition of aromatase and steroid sulfatase (STS) may provide a more effective treatment for hormone-dependent breast cancer than monotherapy against individual enzymes, and several dual aromatase-sulfatase inhibitors (DASIs) have been reported. Three aromatase inhibitors with sub-nanomolar potency, better than
Synthesis and solid-state self-assembly of polyphenols.
European journal of medicinal chemistry, 43(10), 2211-2219 (2008-02-15)
The estrogen receptors (ERs) are attractive targets in the treatment of breast cancer and the development of receptor-based breast cancer imaging agents for diagnostic use in biomedical imaging technique positron emission tomography (PET). Tetrahydroisoquinoline derivatives are a class of selective
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