492876

L-Alanine-¹²C₃

99.9 atom % ¹²C

• Linear Formula: ¹²CH3¹²CH(NH2)¹²CO2H
• CAS Number: 56-41-7
• Molecular Weight: 89.06
• Beilstein: 1720248
• EC Number: 200-273-8
• MDL number: MFCD00198168
• UNSPSC Code: 12352209
• PubChem Substance ID: 24872786

Properties

• description: ¹³C-depleted
• isotopic purity: 99.9 atom % ¹²C
• optical activity: [α]25/D +14.5°, c = 2 in 1 M HCl
• availability: available only in Japan
• mp: 314.5 °C (dec.) (lit.)
• mass shift: depleted
• SMILES string: [12CH3][12C@H](N)[12C](O)=O
• InChI: 1S/C3H7NO2/c1-2(4)3(5)6/h2H,4H2,1H3,(H,5,6)/t2-/m0/s1/i1+0,2+0,3+0
• InChI key: QNAYBMKLOCPYGJ-BWIFZRRMSA-N

Description

Biochem/physiol Actions

L-Alanine is a nonessential amino acid, which is highly concentrated in muscle. It is a key player in the Glucose-Alanine cycle, which enables the removal of pyruvate and glutamate from muscle to the liver. Once in the liver, glucose is regenerated from pyruvate and returned to the muscle while glutamate ultimately participates in the urea cycle to form urea. The Glucose-Alanine cycle aides to conserve ATP in muscle for muscle contraction, while the energy burden of gluconeogenesis is imposed upon the liver. Alanine inhibits pyruvate kinase to regulate gluconeogenesis and glycolysis in order to maintain glucose homeostasis during starvation. Alanine prevents hepatic autophagy. Alanine formation is a result of transamination of glutamate and pyruvate.

Packaging

This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable