442666

(+)-(18-Crown-6)-2,3,11,12-tetracarboxylic acid

97%

• Synonym(s): (2R,3R,11R,12R)-1,4,7,10,13,16-Hexaoxacyclooctadecane-2,3,11,12-tetracarboxylic acid
• Empirical Formula (Hill Notation): C₁₆H₂₄O₁₄
• CAS Number: 61696-54-6
• Molecular Weight: 440.35
• Beilstein: 4240375
• MDL number: MFCD00040514
• UNSPSC Code: 12352005
• PubChem Substance ID: 24867945
• NACRES: NA.22

Properties

• Assay: 97%
• optical activity: [α]20/D +62°, c = 1 in methanol
• mp: 210-212 °C (lit.)
• functional group: carboxylic acid; ether
• SMILES string: OC(=O)[C@@H]1OCCOCCO[C@H]([C@@H](OCCOCCO[C@H]1C(O)=O)C(O)=O)C(O)=O
• InChI: 1S/C16H24O14/c17-13(18)9-10(14(19)20)29-7-3-26-4-8-30-12(16(23)24)11(15(21)22)28-6-2-25-1-5-27-9/h9-12H,1-8H2,(H,17,18)(H,19,20)(H,21,22)(H,23,24)/t9-,10-,11-,12-/m1/s1
• InChI key: FZERLKNAJSFDSQ-DDHJBXDOSA-N

Description

Application

Derived tetracarboxylic acid chloride of this crown ether reacts with meta- and para-xylylene diamines to form chiral captands in high yields. Used as a chiral selector in capillary zone electrophoresis for the separation of a variety of optically active amines. Synthesis of monoamides.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves