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359394

Sigma-Aldrich

Sodium mercaptopyruvate

≥85%, technical grade

Synonym(s):

3-Mercapto-2-oxopropionic acid sodium salt, Mercaptopyruvic acid sodium salt

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About This Item

Linear Formula:
HSCH2COCOONa
CAS Number:
10255-67-1
Molecular Weight:
142.11
Beilstein:
4018548
EC Number:
233-594-7
MDL number:
MFCD00042738
UNSPSC Code:
12352100
PubChem Substance ID:
24862074
NACRES:
NA.22

grade

technical grade

Quality Level

100

Assay

≥85%

form

powder

impurities

<5 wt. % ethanol

mp

200 °C (dec.) (lit.)

storage temp.

2-8°C

SMILES string

[Na+].[O-]C(=O)C(=O)CS

InChI

1S/C3H4O3S.Na/c4-2(1-7)3(5)6;/h7H,1H2,(H,5,6);/q;+1/p-1

InChI key

CODUSAVZTZYYDD-UHFFFAOYSA-M

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Application

Sodium mercaptopyruvate is suitable for use in the thiosulfate sulfurtransferase activity assay.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKBJ4525V
MKBD4833V
MKBG1682V
MKBD4833
02714DJ

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Steven E Patterson et al.
Journal of medicinal chemistry, 56(3), 1346-1349 (2013-01-11)
Current cyanide antidotes are administered by IV infusion, which is suboptimal for mass casualties. Therefore, in a cyanide disaster, intramuscular (IM) injectable antidotes would be more appropriate. We report the discovery of the highly water-soluble sulfanegen triethanolamine as a promising
Adriano Chan et al.
Clinical toxicology (Philadelphia, Pa.), 49(5), 366-373 (2011-07-12)
Cyanide is a component of smoke in residential and industrial fires, and accidental exposure to cyanide occurs in a variety of industries. Moreover, cyanide has the potential to be used by terrorists, particularly in a closed space such as an
M Wróbel et al.
Acta medica Okayama, 54(1), 9-14 (2000-03-10)
The effect of exogenous thyroxine (T4) administration on the activity of rhodanese, cystathionase, and 3-mercaptopyruvate sulfurtransferase (MPST) in the mitochondrial and cytosolic fractions of mouse liver was investigated. Three groups of mice were treated for 6 consecutive days with subcutaneous
W N Valentine et al.
Proceedings of the National Academy of Sciences of the United States of America, 84(5), 1394-1398 (1987-03-01)
Sulfhydryl modification of 22 human erythrocyte enzymes was achieved by exposing intact erythrocytes, hemolysates, and partially purified enzymes to persulfides (RSSH) generated nonenzymatically from cystine in the presence of pyridoxal phosphate and mercaptopyruvate, which donates its sulfur to suitable acceptors
C V Parast et al.
Biochemistry, 34(17), 5712-5717 (1995-05-02)
Pyruvate formate-lyase (PFL) is a glycyl radical-containing enzyme that catalyzes the reversible, nonoxidative conversion of pyruvate and CoA into acetyl-CoA and formate. The radical is located on the alpha-carbon of glycine 734 and is required for catalysis. Two cysteine residues
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