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291366

Sigma-Aldrich

N-(2-Chloroethyl)dibenzylamine hydrochloride

97%

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About This Item

Linear Formula:
(C6H5CH2)2NCH2CH2Cl · HCl
CAS Number:
55-43-6
Molecular Weight:
296.23
EC Number:
200-234-5
MDL number:
MFCD00012518
UNSPSC Code:
12352100
PubChem Substance ID:
24857529
NACRES:
NA.22

Assay

97%

mp

190-193 °C (lit.)

functional group

amine
chloro
phenyl

SMILES string

Cl.ClCCN(Cc1ccccc1)Cc2ccccc2

InChI

1S/C16H18ClN.ClH/c17-11-12-18(13-15-7-3-1-4-8-15)14-16-9-5-2-6-10-16;/h1-10H,11-14H2;1H

InChI key

LZXCEBPGNFLHEQ-UHFFFAOYSA-N

General description

N-(2-Chloroethyl)dibenzylamine hydrochloride is also referred as dibenamine. Mechanism of protection against carbon tetrachloride-induced hepatotoxicity produced by pretreatment with [N-(2-chloroethyl) dibenzylamine] hydrochloride has been investigated. It is a powerful adrenergic blocking agent, is known to modify the pharmacological effects of epinephrine.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCL0563
MKCL0666
MKCD9726
MKBW2348V
MKBL5040V

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Nature of the protection against carbon tetrachloride-induced hepatotoxicity produced by pretreatment with dibenamine (N-(2-chloroethyl)dibenzylamine).
H M Maling et al.
Biochemical pharmacology, 23(10), 1479-1491 (1974-05-15)
Effect of dibenamine (N-(2-chloroethyl) dibenzylamine) on the metabolism of radioactive epinephrine.
R W SCHAYER et al.
The Journal of biological chemistry, 202(1), 39-43 (1953-05-01)

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