Guanidine thiol derivatives--a new class of soluble guanylate cyclase activators--have been studied. Guanidine thiols contain in their molecule both the guanidine and thiol groups which act as donors acceptors of nitric oxide (NO), respectively. The role of the guanidine thiol
The Journal of physiology, 337, 753-768 (1983-04-01)
The effects of intracellular application of three compounds - QX314, N-ethylguanidine and N-octylguanidine - on the acetylcholine-activated ionic channels in chick myoballs were examined. Voltage-clamped myoballs were internally perfused using the suction-pipette technique. Changes in the internal ionic environment of
The Journal of general physiology, 83(6), 901-918 (1984-06-01)
Methyl- and ethylguanidine block the endplate current in frog muscle. Both derivatives blocked inward-going endplate currents without affecting outward endplate currents. Repetitive stimulation that evoked several inward endplate currents enhanced the block, which suggests that these agents interact with open
Questions
Reviews
★★★★★ No rating value
Active Filters
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.