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Key Documents

Z226238

Nucleosil® C8 HPLC Column

5 μm particle size, L × I.D. 25 cm × 4.6 mm

Synonym(s):

Octyl Silica Column

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About This Item

UNSPSC Code:
41115700
eCl@ss:
32110501
NACRES:
SB.52

Agency

suitable for USP L7

Quality Level

product line

Nucleosil®

feature

endcapped: no

manufacturer/tradename

Nucleosil®

extent of labeling

8.5% Carbon loading

parameter

400 bar pressure (5801 psi)

technique(s)

HPLC: suitable

L × I.D.

25 cm × 4.6 mm

surface area

350 m2/g

matrix

octyl

matrix active group

C8 (octyl) phase

particle size

5 μm

pore size

100 Å

separation technique

reversed phase

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Application


  • Determination of melamine in milk and dairy products by high performance liquid chromatography.: This study describes the use of the Nucleosil® C8 HPLC column for determining melamine contamination in dairy products, highlighting its efficiency in food safety applications (Filazi et al., 2012).

  • Validation of a novel, fully automated high throughput high-performance liquid chromatographic/tandem mass Spectrometric method for quantification of pantoprazole in human plasma.: Utilizes Nucleosil® C8 HPLC column to establish a rapid and reliable method for plasma analysis in clinical pharmacokinetic studies (Dotsikas et al., 2010).

  • Simultaneous determination of alprazolam and fluoxetine hydrochloride in tablet formulations by high-performance column liquid chromatography and high-performance thin-layer chromatography.: Demonstrates the versatility of Nucleosil® C8 columns in pharmaceutical analysis, ensuring precise quantification in complex matrices (Patel et al., 2009).

  • Simultaneous estimation of acetylsalicylic acid and clopidogrel bisulfate in pure powder and tablet formulations by high-performance column liquid chromatography and high-performance thin-layer chromatography.: Features the application of Nucleosil® C8 in dual-drug analysis, proving its capability in simultaneous analytical tasks (Patel et al., 2008).

  • Validated HPLC method for determination of amlodipine in human plasma and its application to pharmacokinetic studies.: This research highlights the column′s role in the pharmacokinetic evaluation of cardiovascular drugs, underscoring its reliability and reproducibility (Zarghi et al., 2005).

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Legal Information

Nucleosil is a registered trademark of Macherey-Nagel GmbH & Co. KG

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