SAE0214
Leucoagglutinin from P. vulgaris, recombinant
Expressed in P. pastoris, lyophilized powder, suitable for cell culture
Synonym(s):
PHA-L, Phytohemagglutinin-L, Red Kidney Bean Lectin
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About This Item
UNSPSC Code:
12352202
NACRES:
NA.21
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General description
Lectin from Red Kidney Bean has long been used in a wide variety of applications that require carbohydrate binding including but not limited to T-cell proliferation, leucoagglutination, glycoconjugate capture and more. The native form of lectin from Red Kidney Bean is composed of 2 isolectins (PHA-L and PHA-E) which combine in heterotetromeric combinations that elicit a variety of properties. This recombinant form is strictly the leucoagglutinin (PHA-L) isolectin only, so the erythroagglutinin (PHA-E) isolectin is absent in this product. This allows for more selective performance because there is no chance of PHA-E contamination as seen in native source products.
Biochem/physiol Actions
Kidney bean lectin has a history of being used as a phytohemagglutinin because of its ability to agglutinate blood cells. This isolectin (PHA-L) specficially is the Leucoagglutinin type and can be used for leucoagglutination and as a mitogen. As a lectin, it is known to have some selectivity for binding of β1-6 branched N-glycans.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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Find documentation for the products that you have recently purchased in the Document Library.
A Useful Guide to Lectin Binding: Machine-Learning Directed Annotation of 57 Unique Lectin Specificities
Daniel Bojar
ACS Chemical Biology, 17(11), 2993-3012 (2022)
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