49781
Glycerol solution
83.5-89.5% (T)
Synonym(s):
1,2,3-Propanetriol
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About This Item
Linear Formula:
HOCH2CH(OH)CH2OH · aq
CAS Number:
Molecular Weight:
92.09 (anhydrous basis)
Beilstein:
635685
EC Number:
MDL number:
UNSPSC Code:
50161901
PubChem Substance ID:
NACRES:
NA.28
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Assay
83.5-89.5% (T)
form
viscous liquid
technique(s)
MALDI-MS: suitable
impurities
10.5-16.5% water
ign. residue
≤0.01% (as SO4)
bp
182 °C/20 mmHg (lit.)
density
1.252 g/mL at 25 °C (lit.)
SMILES string
OCC(O)CO
InChI
1S/C3H8O3/c4-1-3(6)2-5/h3-6H,1-2H2
InChI key
PEDCQBHIVMGVHV-UHFFFAOYSA-N
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General description
Glycerol is odourless, colorless, viscous in nature, and exists as a sweet tasting liquid. It can be derived naturally as well as from petrochemical feedstock. Glycerol has a wide variety of applications, and is one of the most valuable and versatile chemical substances in nature. It can be used as an emollient, solvent, sweetening agent, in pharmaceutical formulations, cosmetics, foodstuffs and toiletries. It is very stable and can be easily stored under normal temperature; also it is non-irritating and has no adverse impact to the environment.
Application
Glycerol solution has been used:
- in the preparation of blood mimicking fluid
- in epidermis mimicking films
- as a constituent of nuclei storage buffer
Biochem/physiol Actions
Glycerol has been used as
- a supplement during cell culture of Mycobacterium tuberculosis and Mycobacterium avium.
- a fuel during designing enzymatic biofuel cell.
- a liquid composite matrix with 4-HCCA and 3-aminoquinoline for analysis of neutral and acidic glycans.
- a matrix for fast atom bombardment MS.
- may be employed as liquid matrix for the quantification studies by MALDI (Matrix-assisted laser desorption/ionization mass spectrometry) analysis.
Glycerol is hygroscopic in nature and is soluble in water owing to its three hydrophilic alcoholic hydroxyl groups. It can form both inter- and intramolecular hydrogen bonds, making it a very flexible molecule. The physiologic effect of glycerine is due to cell-mediated immunity, increased IgG production and increased histamine release.
Other Notes
Substrate for the assay of glycerokinase; glycerol dehydratase; glycerol oxidase
WGK
WGK 1
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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B C Johnson et al.
Methods in enzymology, 42, 315-323 (1975-01-01)
H.U. Bergmeyer, ed.
Methods of Enzymatic Analysis, 2, 216-216 (1983)
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