8.55009
NovaSyn®TGR resin
Novabiochem®
Synonym(s):
NovaSyn TGR Solid Support Resin
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About This Item
UNSPSC Code:
12352209
NACRES:
NA.22
Recommended Products
Quality Level
product line
NovaSyn® TG
Novabiochem®
form
beads
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
manufacturer/tradename
Novabiochem®
application(s)
peptide synthesis
functional group
amine
storage temp.
2-8°C
General description
An excellent acid labile support for Fmoc continuous flow and batch synthesis of peptide amides. This resin is prepared from 90 μm NovaSyn TG amino resin by derivatization with the modified Rink linker. It is supplied without Fmoc protection of the linker benzhydrylamine group as this has been found to improve stability. Cleavage is effected with 95% TFA.
Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins
Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins
Application
- An overview of chemical synthesis of antiviral peptides: This study discusses the use of NovaSyn®TGR resin, among others, for peptide synthesis using the Fmoc strategy, particularly highlighting its application in synthesizing antiviral peptides. (Maharani & Muhajir, 2021).
Linkage
Replaces: 01-64-0060
Analysis Note
Color (visual): pale yellow to yellow to beige
Appearance of substance (visual): beads
Loading (determined from the substitution of the Fmoc-Leu loaded resin): 0.20 - 0.30 mmol/g
Swelling Volume (in DMF): lot specific result
The base resin is a PEG-PS copolymer (90 µm) functionalised with the modified Rink linker.
Appearance of substance (visual): beads
Loading (determined from the substitution of the Fmoc-Leu loaded resin): 0.20 - 0.30 mmol/g
Swelling Volume (in DMF): lot specific result
The base resin is a PEG-PS copolymer (90 µm) functionalised with the modified Rink linker.
Legal Information
NOVASYN is a registered trademark of Merck KGaA, Darmstadt, Germany
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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