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Key Documents

850745P

Avanti

14:0 PE

Avanti Research - A Croda Brand

Synonym(s):

1,2-ditetradecanoyl-sn-glycero-3-phosphoethanolamine; DMPE; PE(14:0/14:0); 110632

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About This Item

Empirical Formula (Hill Notation):
C33H66NO8P
CAS Number:
Molecular Weight:
635.85
UNSPSC Code:
51191904
NACRES:
NA.25

description

1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 g (850745P-1g)
pkg of 1 × 200 mg (850745P-200mg)
pkg of 1 × 25 mg (850745P-25mg)
pkg of 1 × 500 mg (850745P-500mg)

manufacturer/tradename

Avanti Research - A Croda Brand

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O

InChI

1S/C33H66NO8P/c1-3-5-7-9-11-13-15-17-19-21-23-25-32(35)39-29-31(30-41-43(37,38)40-28-27-34)42-33(36)26-24-22-20-18-16-14-12-10-8-6-4-2/h31H,3-30,34H2,1-2H3,(H,37,38)/t31-/m1/s1

InChI key

NEZDNQCXEZDCBI-WJOKGBTCSA-N

General description

Phosphatidylethanolamine (PE) is an abundant phospholipid, found in the cells of mammals.

Application

1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine (14:0 PE):
  • has been used as a phospholipid (PL) internal standard in hydrophilic interaction liquid chromatography tandem mass spectrometry (HILIC-LC-MS/MS)
  • has been used as an internal lipid standard to correct the reproducibility in matrix-assisted laser desorption/ionization Fourier transform ion cyclotron resonance mass spectrometry (MALDI FT-ICR MS) analysis
  • may be used in proteoliposomes for planar supported lipid bilayer formation
  • may be used as a biotinylated internal standard to measure externalization of aminophospholipids (APLs) using mass spectrometry (MS)

Biochem/physiol Actions

Phosphatidylethanolamine (PE) plays a key role in the activity of respiratory complexes. PE also participates in the initiation of autophagy.

Packaging

20 mL Clear Glass Screw Cap Vial (850745P-1g)
20 mL Clear Glass Screw Cap Vial (850745P-500mg)
5 mL Amber Glass Screw Cap Vial (850745P-200mg)
5 mL Amber Glass Screw Cap Vial (850745P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Alex J B Kreutzberger et al.
Biophysical journal, 115(9), 1755-1761 (2018-10-22)
Intramembrane proteases hydrolyze peptide bonds within the membrane as a regulatory paradigm that is conserved across all forms of cellular life. Many of these enzymes are thought to be oligomeric, and that their resulting quaternary interactions form the basis of
Paulina Perczyk et al.
Biochimica et biophysica acta. Biomembranes, 1862(2), 183136-183136 (2019-11-22)
Soil fungi play an important role in the environment decomposing dead organic matter and degrading persistent organic pollutants (POP). The presence of hydrophobic POP in the soil and membrane-lytic substances excreted by competing microorganism to the soil solution is the
Paulina Perczyk et al.
Biochimica et biophysica acta. Biomembranes, 1862(6), 183239-183239 (2020-03-03)
Soil bacteria are decomposer organisms crucial for the biodegradation of organic pollutants, mineralization of dead organic matter and the turnover of biogenic elements. In their environment they are constantly exposed to membrane-lytic enzymes emitted to the soil by other microorganisms
Luke S Evans et al.
Biochimica et biophysica acta. Biomembranes, 1862(9), 183343-183343 (2020-05-18)
Lipidic bicelles have been widely used for the analysis of integral membrane proteins where their spontaneous alignment in an magnetic field has been exploited for oriented sample solid-state NMR studies. Many of their physical properties however make them well suited
Ondřej Peterka et al.
Biochimica et biophysica acta. Molecular and cell biology of lipids, 1865(5), 158634-158634 (2020-01-25)
Ultrahigh-performance supercritical fluid chromatography - mass spectrometry (UHPSFC/MS), ultrahigh-performance liquid chromatography - mass spectrometry (UHPLC/MS), and matrix-assisted laser desorption/ionization (MALDI) - MS techniques were used for the lipidomic characterization of exosomes isolated from human plasma. The high-throughput methods UHPSFC/MS and

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