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A78209

Sigma-Aldrich

3-Aminopyridine

99%

Synonym(s):

3-Pyridinamine

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About This Item

Empirical Formula (Hill Notation):
C5H6N2
CAS Number:
462-08-8
Molecular Weight:
94.11
Beilstein:
105692
EC Number:
207-322-2
MDL number:
MFCD00006400
UNSPSC Code:
12352100
PubChem Substance ID:
24891284
NACRES:
NA.22

Assay

99%

form

flakes

bp

248 °C (lit.)

mp

60-63 °C (lit.)

SMILES string

Nc1cccnc1

InChI

1S/C5H6N2/c6-5-2-1-3-7-4-5/h1-4H,6H2

InChI key

CUYKNJBYIJFRCU-UHFFFAOYSA-N

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Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT RE 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

190.4 °F - closed cup

Flash Point(C)

88 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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B Barna et al.
Acta biologica Hungarica, 50(1-3), 257-267 (1999-11-26)
The effect of GYKI 52466, a selective, non-competitive antagonist of the AMPA glutamate receptor subtype was investigated on the development, expression and propagation of 3-aminopyridine-induced cortical ictal activity, both in the primary and secondary focus. In one group of animals
Effects of chronic, intrauterine organic and inorganic mercury intoxication on the epileptogenicity of developing rat.
B Barna et al.
Central European journal of public health, 8 Suppl, 73-75 (2000-08-16)
M Szente et al.
Brain research, 413(2), 368-373 (1987-06-16)
Intracellular recordings were obtained from neurons in the motor cortex of anesthetized cats in order to examine membrane and synaptic processes involved in aminopyridine (AP)-induced ictal seizure activity. Depolarizing and hyperpolarizing membrane potential sequences which behaved as large, synchronized excitatory
M B Szente et al.
Acta physiologica Hungarica, 81(2), 159-174 (1993-01-01)
Effects of 3-aminopyridine (3-Ap) applied intracellularly into electrophysiologically identified cortical neurons in the cat motor cortex were studied. Actions on the membrane and firing activity properties, excitatory and inhibitory postsynaptic responses were investigated. Intracellular microelectrode techniques and single electrode voltage
J Pearce et al.
Journal of neurocytology, 15(2), 241-252 (1986-04-01)
The fine structure of identified neuromuscular synapses of the single excitatory axon to the distal accessory flexor muscle in lobster limbs was examined with freeze-fracture and serial thin-section electron microscopy. The latter technique reveals presynaptic dense bars with synaptic vesicles
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