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860077

Sigma-Aldrich

Phospho(enol)pyruvic acid monopotassium salt

99%

Synonym(s):

mono-Potassium phosphoenolpyruvate, PEP monopotassium salt, PEP-K, Phospho(enol)pyruvate potassium salt

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About This Item

Linear Formula:
KOP(O)(OH)OC(=CH2)CO2H
CAS Number:
4265-07-0
Molecular Weight:
206.13
Beilstein:
4603446
EC Number:
224-247-0
MDL number:
MFCD00044476
UNSPSC Code:
12352100
PubChem Substance ID:
24888496
NACRES:
NA.22

Quality Level

100

Assay

99%

form

powder

mp

175 °C (dec.) (lit.)

storage temp.

−20°C

SMILES string

[K+].OC(=O)C(=C)OP(O)([O-])=O

InChI

1S/C3H5O6P.K/c1-2(3(4)5)9-10(6,7)8;/h1H2,(H,4,5)(H2,6,7,8);/q;+1/p-1

InChI key

SOSDSEAIODNVPX-UHFFFAOYSA-M

Application

Substrate for many kinase reactions.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Stefan Niekamp et al.
Nature methods, 17(4), 437-441 (2020-03-24)
Photobleaching limits extended imaging of fluorescent biological samples. We developed DNA-based 'FluoroCubes' that are similar in size to the green fluorescent protein, have single-point attachment to proteins, have a ~54-fold higher photobleaching lifetime and emit ~43-fold more photons than single
Ernesto Arias-Palomo et al.
Molecular cell, 74(1), 173-184 (2019-02-25)
In cells, dedicated AAA+ ATPases deposit hexameric, ring-shaped helicases onto DNA to initiate chromosomal replication. To better understand the mechanisms by which helicase loading can occur, we used cryo-EM to determine sub-4-Å-resolution structures of the E. coli DnaB⋅DnaC helicase⋅loader complex with
Jemila C Kester et al.
Journal of bacteriology, 203(4) (2020-11-25)
The ClpP1P2 proteolytic complex is essential in Mycobacterium tuberculosis Proteolysis by ClpP1P2 requires an associated ATPase, either ClpX or ClpC1. Here, we sought to define the unique contributions of the ClpX ATPase to mycobacterial growth. We formally demonstrated that ClpX
Hui Hong et al.
Cell chemical biology, 26(4), 493-501 (2019-02-05)
Malayamycin A is an unusual bicyclic C-nucleoside, with interesting antiviral, antifungal, and anticancer bioactivity. We report here the discovery and characterization of the biosynthetic pathway to malayamycin by using genome mining of near-identical clusters both from the known producer Streptomyces
Juraj Ahel et al.
eLife, 9 (2020-06-24)
RNF213 is the major susceptibility factor for Moyamoya disease, a progressive cerebrovascular disorder that often leads to brain stroke in adults and children. Characterization of disease-associated mutations has been complicated by the enormous size of RNF213. Here, we present the
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