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384003

Sigma-Aldrich

2-Bromo-5-methoxybenzoic acid

98%

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About This Item

Linear Formula:
BrC6H3(OCH3)CO2H
CAS Number:
22921-68-2
Molecular Weight:
231.04
EC Number:
245-329-2
MDL number:
MFCD00020214
UNSPSC Code:
12352100
PubChem Substance ID:
24863642
NACRES:
NA.22

Quality Level

100

Assay

98%

form

solid

mp

157-159 °C (lit.)

SMILES string

COc1ccc(Br)c(c1)C(O)=O

InChI

1S/C8H7BrO3/c1-12-5-2-3-7(9)6(4-5)8(10)11/h2-4H,1H3,(H,10,11)

InChI key

ODHJOROUCITYNF-UHFFFAOYSA-N

Related Categories

General description

2-Bromo-5-methoxybenzoic acid is a benzoic acid derivative. Synthesis of 2-bromo-5-methoxybenzoic acid and its characterization by HNMR has been reported.

Application

2-Bromo-5-methoxybenzoic acid is suitable for use in the syntheses of urolithin derivatives. It may be used in the synthesis of the following:
  • substituted aminobenzacridines
  • 8-chloro-2-methoxydibenzo[b,f]thiepin-10(11H)-one and its 3-methoxy derivative
  • isoindolinone derivatives

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Potential metabolites of clorotepin: 2-and 3-hydroxy derivatives of 8-chloro-10-(4-methylpiperazino)-10, 11-dihydrodibenzo [b, f] thiepin and their methyl ethers.
Sindelar, K., et al.
Collection of Czechoslovak Chemical Communications, 39(12), 3548-3559 (1974)
Lynn S Adams et al.
Cancer prevention research (Philadelphia, Pa.), 3(1), 108-113 (2010-01-07)
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Design, synthesis and biological evaluation of the novel isoindolinone derivatives.
Liu J, et al.
J. Chem. Res. (M), 6(9), 256-260 (2014)
Synthesis of substituted aminobenzacridines.
G B BACHMAN et al.
Journal of the American Chemical Society, 68, 1599-1602 (1946-08-01)
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The detection and sensing of environmentally crucial metal ions has always been of great significance in various fields such as biological and environmental cycles. Our previous studies have indicated a new coumarin based lactone, Urolithin B (i.e., 3-Hydroxy[c]chromen-6-one) as a

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