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376914

Sigma-Aldrich

Poly(methyl methacrylate-co-methacrylic acid)

average Mw ~34,000 by GPC, average Mn ~15,000 by GPC

Synonym(s):

Poly(methacrylic acid-co-methyl methacrylate)

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About This Item

CAS Number:
25086-15-1
MDL number:
MFCD00243185
UNSPSC Code:
12162002
PubChem Substance ID:
24863477
NACRES:
NA.23
Pricing and availability is not currently available.

feed ratio

1:0.016 (methyl methacrylate:methacrylic acid)

mol wt

average Mn ~15,000 by GPC
average Mw ~34,000 by GPC

inherent viscosity

0.19 dL/g(lit.)

transition temp

Tg 105 °C

SMILES string

O(C)C(=O)C(=C)C.OC(=O)C(=C)C

InChI

1S/C5H8O2.C4H6O2/c1-4(2)5(6)7-3;1-3(2)4(5)6/h1H2,2-3H3;1H2,2H3,(H,5,6)

InChI key

IWVKTOUOPHGZRX-UHFFFAOYSA-N

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Application

  • Ultrafine Nanoparticles of Poly(Methyl Methacrylate-co-Methacrylic Acid) Loaded with Aspirin: This study focuses on the preparation and potential therapeutic applications of biocompatible nanoparticles loaded with aspirin, highlighting their suitability for medical use (López-Muñoz et al., 2019).
  • Biocompatible and biodegradable ultrafine nanoparticles of poly (methyl methacrylate-co-methacrylic acid) prepared via semicontinuous heterophase: Discusses the synthesis of biodegradable nanoparticles for potential biomedical applications, emphasizing their eco-friendly nature and suitability for drug delivery systems (Saade et al., 2016).
  • Synthesis and characteristics of poly(methyl methacrylate‐co‐methacrylic acid)/poly(methacrylic acid‐co‐N‐isopropylacrylamide) thermosensitive semi‐hollow latex: Explores the unique properties of thermosensitive latex particles for advanced material applications, potentially useful in smart drug delivery systems (Lee et al., 2014).
  • Preparation and release behavior of poly(methyl methacrylate-co-methacrylic acid)-based electrospun nanofibrous mats loaded with doxorubicin: Examines the use of polymeric nanofibers for controlled drug release, particularly for cancer treatment, demonstrating the versatility of poly(methyl methacrylate-co-methacrylic acid) in pharmaceutical applications (López-Muñoz et al., 2023).

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKBG3620V
MKBG3616V
MKBD4926
MKBD4927
02414EJ

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Suprita A Tawde et al.
Vaccine, 30(38), 5675-5681 (2012-07-04)
Ovarian cancer is the fifth most leading cause of cancer related deaths in women in the US. Customized immunotherapeutic strategies may serve as an alternative method to control the recurrence or progression of ovarian cancer and to avoid severe adverse
Pravin K Pawar et al.
Acta pharmaceutica (Zagreb, Croatia), 62(1), 93-104 (2012-04-05)
The objective of the present investigation was to prepare and evaluate ocular inserts of moxifloxacin. An ocular insert was made from an aqueous dispersion of moxifloxacin, sodium alginate, polyvinyl alcohol, and dibutyl phthalate by the film casting method. The ocular
Prathap Nagaraja Shastri et al.
Drug development and industrial pharmacy, 39(2), 164-175 (2012-05-18)
Oral delivery of proteins has been a challenging as well as rapidly developing field. To implement mixture design of experiment to develop enteric-coated microparticles containing bovine serum albumin. Microparticles were prepared using Buchi Spray Dryer 191. Simplex lattice mixture design
Yan Zhang et al.
International journal of pharmaceutics, 436(1-2), 341-350 (2012-07-07)
In the present study thiolated Eudragit L100 (Eul) based polymeric nanoparticles (NPs) were employed to develop an oral insulin delivery system. Sulfydryl modification was achieved by grafting cysteine to the carboxylic acid group of Eudragit L100, which displayed maximum conjugate
Katia P Seremeta et al.
Colloids and surfaces. B, Biointerfaces, 102, 441-449 (2012-09-27)
The design of simple and scalable drug delivery systems to target the central nervous system (CNS) could represent a breakthrough in the addressment of the HIV-associated neuropathogenesis. The intranasal (i.n.) route represents a minimally invasive strategy to surpass the blood-brain
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Questions

1–4 of 4 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  3. メタクリル酸メチルとメタクリル酸の共重合比はいくつですか？

    1 answer

    1. Unfortunately, the PMMA: PMAA ratio for this item is not tested. The feed ratio is 1:0.016 (methyl methacrylate:methacrylic acid); however, there is no information available on the PMMA: PMAA ratio.

      Helpful?

  4. What is the XPS database for Poly (Acrylic acid-co-Methyl methacrylate)?

    1 answer

    1. An XPS data file is not currently available for this product.

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