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L4530

Sigma-Aldrich

Latex beads, carboxylate-modified polystyrene, fluorescent yellow-green

aqueous suspension, 2.0 μm mean particle size

Synonym(s):

Fluorescent Latex Beads

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About This Item

MDL number:
MFCD00131492
UNSPSC Code:
12162002
NACRES:
NA.25
Pricing and availability is not currently available.

form

aqueous suspension

Quality Level

100

composition

Solids, 2.5%

technique(s)

cell based assay: suitable

mean particle size

2.0 μm

fluorescence

λex ~470 nm; λem ~505 nm

application(s)

cell analysis

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Application

Carboxylate-modified polystyrene latex beads have been used to collect morphofunctional data about the immune systems of Carabus lefebvrei, a helicophagous Italian endemic ground beetle often used as an indicator of the habitat quality of the Apennines mountain forests. Carboxylate-modified polystyrene latex beads have also been used to inform comparative studies on immunity defense mechanisms of adults and larvae of the coleopteran Cetonischema aeruginosa and to investigate the phagocytic activity of cultured rat thyroid cells.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
MKCW7183
MKCS8659
MKCQ9621
MKCN4020
MKCK1496

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Xiujie Li et al.
The American journal of pathology, 170(1), 399-415 (2007-01-04)
We previously reported that truncation of Notch1 (N1) by provirus insertion leads to overexpression of both the intracellular (N1(IC)) and the extracellular (N1(EC)) domains. We produced transgenic (Tg) mice expressing N1(EC) in T cells and in cells of the myeloid
Shawna L Semple et al.
Microbial pathogenesis, 139, 103910-103910 (2019-12-07)
The life cycle of Flavobacterium psychrophilum (Fp), the causative agent of bacterial coldwater disease (BCWD) and rainbow trout fry syndrome (RTFS), appears to involve interactions with spleen and head kidney macrophages. To develop an in vitro model for studying this
Yannyk Bourquin et al.
Lab on a chip, 11(16), 2725-2730 (2011-07-05)
The diagnosis of infectious diseases in the Developing World is technologically challenging requiring complex biological assays with a high analytical performance, at minimal cost. By using an opto-acoustic immunoassay technology, integrating components commonly used in mobile phone technologies, including surface
Soraat Amphan et al.
Fish & shellfish immunology, 87, 120-128 (2019-01-01)
β-glucan is one of the most potent immunostimulants enhancing innate immune activity, disease resistance and growth performance of many aquatic organisms. Nevertheless, there are few studies on feeding regimens of β-glucan that correlate to immune response and disease resistance and
S L Mueller-Ortiz et al.
Infection and immunity, 69(12), 7501-7511 (2001-11-14)
Mycobacterium tuberculosis and Mycobacterium avium are facultative intracellular pathogens that are able to survive and replicate in mononuclear phagocytes. Human complement component C3 has previously been shown to mediate attachment and phagocytosis of these bacteria by mononuclear phagocytes. In this
View All Related Papers

Questions

1–3 of 3 Questions  

  1. L4530-1ML 이제품 1ml당 비드 개수를 알고 싶습니다. 보관 온도및 어두운 환경에서 보관해야 하는지도 궁금합니다.

    1 answer

    1. Concentration is aqueous suspension of 2.5% w/v as indicated in the CoA. Estimated amount of particles in 1mL of 2.5% of 1.9um particles is calculated to be 6.66E9 particles/mL. Recommended storage is 2–8 °C

      Helpful?

  2. Would this product work to investigate the phagocytic activity of cultured primary human macrophages?

    1 answer

    1. This product is not tested for use in specific applications. However, there are several publications regarding the use of this item in phagocytosis indicating suitability. Please see the links below to review additional information:

      Macrophage migration and phagocytosis are controlled by Kindlin-3 link to cytoskeleton
      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203317/

      Phagocytic Activity of FRTL-5 Rat Thyroid Follicular Cells as Measured by Ingestion of Fluorescent Latex Beads
      https://www.sciencedirect.com/science/article/pii/S0014482785712633?via%3Dihub

      Helpful?

  3. What is the concentration of product L4530?

    1 answer

    1. The estimated amount of particles in 1mL of 2.5% of 1.9um particles is 6.66E9 particles/mL.

      Helpful?

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