Skip to Content
Merck
All Photos(2)

Documents

D201863

Sigma-Aldrich

1,4-Dioxane

ReagentPlus®, ≥99%, contains ≤25 ppm BHT as stabilizer

Synonym(s):

Diethylene oxide, Dioxane

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Empirical Formula (Hill Notation):
C4H8O2
CAS Number:
123-91-1
Molecular Weight:
88.11
Beilstein:
102551
EC Number:
204-661-8
MDL number:
MFCD00006571
UNSPSC Code:
12352005
PubChem Substance ID:
329798726
NACRES:
NA.21

vapor density

3 (vs air)

Quality Level

100

vapor pressure

27 mmHg ( 20 °C)
40 mmHg ( 25 °C)

product line

ReagentPlus®

Assay

≥99%

form

liquid

autoignition temp.

356 °F

contains

≤25 ppm BHT as stabilizer

expl. lim.

22 %

technique(s)

thin layer chromatography (TLC): suitable

refractive index

n20/D 1.422 (lit.)

pH

6.0-8 (20 °C, 500 g/L)

bp

100-102 °C (lit.)

mp

10-12 °C (lit.)

density

1.034 g/mL at 25 °C (lit.)

SMILES string

C1COCCO1

InChI

1S/C4H8O2/c1-2-6-4-3-5-1/h1-4H2

InChI key

RYHBNJHYFVUHQT-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

1,4-Dioxane can be used as a solvent:
  • To synthesize 1,3-diamines and amino alcohols via 2-azaallyl anion benzylic ring-opening of aziridines.
  • In the RAFT polymerization of acryclic acid.
  • In the synthesis of cross-linked triblock copolymer hydrogels.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Statements

H225,H319,H335,H350

Hazard Classifications

Carc. 1B - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

Target Organs

Respiratory system

Supplementary Hazards

EUH019,EUH066

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

51.8 °F - closed cup

Flash Point(C)

11 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Photoactive rose bengal-based latex via RAFT emulsion polymerization-induced self-assembly
Boussiron C, et al.
Open Journal of Polymer Chemistry, 12, 134-147 (2021)
High-toughness polycation cross-linked triblock copolymer hydrogels
Chen Y, et al.
Macromolecules, 50, 3637-3646 (2017)
Yimu Zhao et al.
Advanced healthcare materials, 8(5), e1801187-e1801187 (2019-02-10)
Due to escalating drug developmental costs and limitations of cardiotoxicity screening, there is an urgent need to develop robust in vitro 3D tissue culture platforms that can both facilitate the culture of human cardiac tissues and provide noninvasive functional readouts
Xiaohua Liu et al.
Biomaterials, 31(2), 259-269 (2009-09-29)
It remains a challenge to synthesize functional materials that can develop advanced scaffolding architectures for tissue engineering. In this study, a series of biodegradable amphiphilic poly(hydroxyalkyl (meth)acrylate)-graft-poly(l-lactic acid) (PHAA-g-PLLA) copolymers have been synthesized and fabricated into nano-fibrous scaffolds. These copolymers
Joshua J Pacheco et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(23), 8363-8367 (2014-06-10)
Terephthalic acid (PTA), a monomer in the synthesis of polyethylene terephthalate (PET), is obtained by the oxidation of petroleum-derived p-xylene. There is significant interest in the synthesis of renewable, biomass-derived PTA. Here, routes to PTA starting from oxidized products of
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service