PHL80822

Linarin

phyproof^® Reference Substance

• Synonym(s): 5,7-Dihydroxy 4′-methoxyflavone 7-rutinoside, 7-((6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl)oxy)-5-hydroxy-2-(4-methoxyphenyl)-4H-benzopyran-4-one, Acacetin-7-rutinoside, Buddleoside, Linarigenin glycoside
• Empirical Formula (Hill Notation): C₂₈H₃₂O₁₄
• CAS Number: 480-36-4
• Molecular Weight: 592.55
• MDL number: MFCD00151178
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: primary reference standard
• product line: phyproof^® Reference Substance
• Assay: ≥90.0% (HPLC)
• manufacturer/tradename: PhytoLab
• application(s): food and beverages
• format: neat
• SMILES string: O1[C@H]([C@@H]([C@@H]([C@H]([C@@H]1C)O)O)O)OC[C@H]2O[C@H]([C@@H]([C@H]([C@@H]2O)O)O)Oc3cc4[o]c(c[c](c4c(c3)O)=O)c5ccc(cc5)OC
• InChI: 1S/C28H32O14/c1-11-21(31)23(33)25(35)27(39-11)38-10-19-22(32)24(34)26(36)28(42-19)40-14-7-15(29)20-16(30)9-17(41-18(20)8-14)12-3-5-13(37-2)6-4-12/h3-9,11,19,21-29,31-36H,10H2,1-2H3/t11-,19+,21-,22+,23+,24-,25+,26+,27+,28+/m0/s1
• InChI key: YFVGIJBUXMQFOF-PJOVQGMDSA-N

Description

General description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Application

• Linarin as a Neuroprotective Agent Studies: Linarin demonstrated potential neuroprotective effects, ameliorating ischemia-reperfusion injury by inhibiting endoplasmic reticulum stress targeting AKR1B1, which suggests its applicability in the development of treatments for neurodegenerative disorders (Zhang et al., 2024).


• Anti-inflammatory Effects of Linarin in Biochemistry: The anti-inflammatory properties of Linarin make it a significant compound for research in pharmacological sciences, as it might lead to new insights into the modulation of inflammatory pathways in chronic diseases (Cheriet et al., 2024).


• Linarin in Chromatography and Spectrometry Analysis: As a chromatography standard, Linarin is essential for developing analytical methods that ensure the quality control of medicinal plants and herbal products, which is key for natural product research and drug development (Gontar et al., 2024).

Legal Information

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable