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Key Documents

BP725

Alverine citrate

British Pharmacopoeia (BP) Reference Standard

Synonym(s):

Alverine citrate salt, N-Ethyl-3,3′-diphenyldipropylamine, NSC 35459

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About This Item

Empirical Formula (Hill Notation):
C20H27N · C6H8O7
CAS Number:
Molecular Weight:
473.56
MDL number:
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

alverine

form

crystalline powder

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

BP

application(s)

pharmaceutical
pharmaceutical small molecule

format

neat

SMILES string

OC(=O)CC(O)(CC(O)=O)C(O)=O.CCN(CCCc1ccccc1)CCCc2ccccc2

InChI

1S/C20H27N.C6H8O7/c1-2-21(17-9-15-19-11-5-3-6-12-19)18-10-16-20-13-7-4-8-14-20;7-3(8)1-6(13,5(11)12)2-4(9)10/h3-8,11-14H,2,9-10,15-18H2,1H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)

InChI key

RYHCACJBKCOBTJ-UHFFFAOYSA-N

Gene Information

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Alverine citrate BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Alverine Capsules
  • Used for studies of pharmacological activity including:
    • Synergism with fluconazole against Saccharomyces cerevisiae and Candida albicans
    • Efficacy of combination with simeticone on abdominal pain associated with irritable bowel syndrome
    • Nutrient-sensitized screening for drugs that shift energy metabolism from mitochondrial respiration to glycolysis
    • Drug effects viewed from a signal transduction network perspective
    • Enhanced cytotoxic effect of proteasome inhibitor MG132
    • Mechanism of action on phasic smooth muscles

    Packaging

    Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

    Other Notes

    Sales restrictions may apply.

    Storage Class Code

    11 - Combustible Solids

    WGK

    WGK 3

    Flash Point(F)

    Not applicable

    Flash Point(C)

    Not applicable


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