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Key Documents

855676P

Avanti

17:0 Lyso PC

Avanti Research - A Croda Brand

Synonym(s):

1-heptadecanoyl-sn-glycero-3-phosphocholine; PC(17:0/0:0)

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About This Item

Empirical Formula (Hill Notation):
C25H52NO7P
CAS Number:
Molecular Weight:
509.66
MDL number:
UNSPSC Code:
51191904
NACRES:
NA.25

description

1-heptadecanoyl-2-hydroxy-sn-glycero-3-phosphocholine

Assay

>99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC)

form

powder

packaging

pkg of 1 × 200 mg (855676P-200mg)
pkg of 1 × 25 mg (855676P-25mg)

manufacturer/tradename

Avanti Research - A Croda Brand

shipped in

dry ice

storage temp.

−20°C

SMILES string

O[C@](COP([O-])(OCC[N+](C)(C)C)=O)([H])COC(CCCCCCCCCCCCCCCC)=O

InChI

1S/C25H52NO7P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-25(28)31-22-24(27)23-33-34(29,30)32-21-20-26(2,3)4/h24,27H,5-23H2,1-4H3/t24-/m1/s1

InChI key

SRRQPVVYXBTRQK-XMMPIXPASA-N

Application


  • Serum lipids profiling perturbances in patients with ischemic heart disease and ischemic cardiomyopathy.: This study examines alterations in serum lipid profiles among patients with ischemic conditions, potentially highlighting roles of specific lipid molecules like 17:0 Lyso PC in the pathology of these diseases (Yang et al., 2020).

Packaging

5 mL Amber Glass Screw Cap Vial (855676P-200mg)
5 mL Amber Glass Screw Cap Vial (855676P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Poorna C R Yalagala et al.
Molecular nutrition & food research, 64(12), e2000059-e2000059 (2020-04-19)
Currently available omega-3 fatty acid supplements do not enrich the docosahexaenoic acid (DHA) of the adult brain because they are absorbed as triacylglycerol, whereas the transporter at the blood brain barrier requires lysophosphatidylcholine (LPC)-DHA. The hypothesis that treatment of krill
Hiroyasu Sato et al.
Cell reports, 31(5), 107579-107579 (2020-05-07)
Polyunsaturated fatty acids (PUFAs) confer health benefits by preventing inflammation and obesity and by increasing thermogenesis in brown and beige adipocytes. As well as being supplied exogenously as nutrients, PUFAs are largely stored in membrane glycerophospholipids and released by phospholipase
Michael M Dubreuil et al.
Cell reports, 30(5), 1417-1433 (2020-02-06)
Reactive oxygen species (ROS) play critical roles in metabolism and disease, yet a comprehensive analysis of the cellular response to oxidative stress is lacking. To systematically identify regulators of oxidative stress, we conducted genome-wide Cas9/CRISPR and shRNA screens. This revealed a detailed
Melania Gaggini et al.
International journal of molecular sciences, 20(24) (2020-01-01)
Metabolomics/lipidomics are important tools to identify novel biomarkers associated with liver damage. Patients with chronic liver disease (CLD) and hepatitis C virus (HCV) infection often have alterations in glucose, lipid and protein metabolism. The aim of this study was to
Jordon M Inloes et al.
Biochemistry, 57(39), 5759-5767 (2018-09-18)
Deleterious mutations in the serine hydrolase DDHD domain containing 1 (DDHD1) cause the SPG28 subtype of the neurological disease hereditary spastic paraplegia (HSP), which is characterized by axonal neuropathy and gait impairments. DDHD1 has been shown to display PLA1-type phospholipase

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