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17988

Sigma-Aldrich

DL-β-Leucine

≥98.0% (NT)

Synonym(s):

(±)-3-Amino-4-methylpentanoic acid, (±)-3-Amino-4-methylvaleric acid

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About This Item

Empirical Formula (Hill Notation):
C6H13NO2
CAS Number:
Molecular Weight:
131.17
Beilstein:
1747371
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:

Assay

≥98.0% (NT)

application(s)

peptide synthesis

SMILES string

CC(C)C(N)CC(O)=O

InChI

1S/C6H13NO2/c1-4(2)5(7)3-6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)

InChI key

GLUJNGJDHCTUJY-UHFFFAOYSA-N

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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J M Poston
The Journal of biological chemistry, 255(21), 10067-10072 (1980-11-10)
Circulating levels of beta-leucine are elevated in the cobalamin-deficient state of pernicious anemia. Levels of leucine, on the other hand, are much lower. It is proposed that leucine 2,3-aminomutase, the cobalamin-dependent enzyme that catalyzes the interconversion of leucine and beta-leucine
The synthesis and detection of beta leucines.
S R Sylvester et al.
Proceedings of the Western Pharmacology Society, 24, 117-117 (1981-01-01)
N E Ward et al.
The Journal of nutrition, 118(2), 159-164 (1988-02-01)
This study was designed to investigate a postulated relationship between vitamin B-12 and leucine metabolism in mature domestic chickens. Plasma amino acid analysis revealed the presence of beta-leucine at a concentration of 60 to 80 mumol/l. After 425 d on
Beta-leucine and the beta-keto pathway of leucine metabolism.
J M Poston
Advances in enzymology and related areas of molecular biology, 58, 173-189 (1986-01-01)
P E Coffey et al.
Chemical communications (Cambridge, England), (22)(22), 2330-2331 (2002-09-21)
Poly-beta-leucines have been evaluated as catalysts for the Juliá-Colonna asymmetric epoxidation of enones; the beta 3-isomer was found to be an effective catalyst for the epoxidation of chalcone (70% ee) and some analogues.

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