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G5384

Sigma-Aldrich

Gelatin-Agarose

saline suspension

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About This Item

MDL number:
UNSPSC Code:
41106500
NACRES:
NA.56

biological source

protein from Porcine skin

form

saline suspension

extent of labeling

≥3 mg per mL

matrix

cross-linked 4% beaded agarose

matrix activation

cyanogen bromide

matrix attachment

amino

matrix spacer

1 atom

storage temp.

2-8°C

Application

Gelatin-Agarose has been used:
  • in the isolation of exosomes from human plasma
  • to obtain fluorescent labeled enzyme For fluorescence photobleaching recovery (FPR) experiments
  • in the purifaction of matrix metalloproteinase-9 by affinity chromatography
Gelatin-agarose is an agarose in saline suspension used for affinity chromatography, protein chromatography and specialty resins. Gelatin-agarose has been used in studies informing pathology-related processes of tissue remodeling as well as sperm-egg interactions in mammals.

Physical form

Suspension in 0.5 M NaCl containing preservative

Storage Class Code

10 - Combustible liquids

WGK

WGK 3


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Substrate Recognition by Gelatinase A: The C-Terminal Domain Facilitates Surface Diffusion
Ivan EC, et al.
Biophysical Journal, 81(4), 2370-2377 (2001)
Toshiro Matsunaga et al.
Circulation, 105(18), 2185-2191 (2002-05-08)
The in vivo mechanism by which inhibition of NO synthase impairs ischemia-induced coronary vascular growth is unknown. We hypothesized that production of the growth inhibitor angiostatin increases during decreased NO production, blunting angiogenesis and collateral growth. Measurements were made in
Christophe Noll et al.
The Journal of nutritional biochemistry, 22(9), 856-864 (2010-12-28)
Hyperhomocysteinemia leads to several clinical manifestations and, particularly, liver disease. Lowering homocysteine through nutrition or other means might offer preventive or therapeutic benefits. Polyphenols are natural compounds known for their antioxidant and healing properties for vessels. In a previous study
Melatonin inhibits matrix metalloproteinase-9 activity by binding to its
active site
Deep SR, et al.
Journal of Pineal Research (2012)
Yingshi Ouyang et al.
Placenta, 47, 86-95 (2016-10-27)
Primary human trophoblasts release a repertoire of extracellular vesicles (EVs). Among them are nano-sized exosomes, which we found to suppress the replication of a wide range of diverse viruses. These exosomes contain trophoblastic microRNAs (miRNAs) that are expressed from the

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