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Zoxamide

PESTANAL®, analytical standard

Synonym(s):

3,5-Dichloro-N-(3-chloro-1-ethyl-1-methyl-2-oxopropyl)-4-methylbenzamide

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About This Item

Empirical Formula (Hill Notation):
C14H16Cl3NO2
CAS Number:
Molecular Weight:
336.64
Beilstein:
11413911
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

agriculture
environmental

format

neat

SMILES string

CCC(C)(NC(=O)c1cc(Cl)c(C)c(Cl)c1)C(=O)CCl

InChI

1S/C14H16Cl3NO2/c1-4-14(3,12(19)7-15)18-13(20)9-5-10(16)8(2)11(17)6-9/h5-6H,4,7H2,1-3H3,(H,18,20)

InChI key

SOUGWDPPRBKJEX-UHFFFAOYSA-N

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General description

Zoxamide belongs to the benzamide class of fungicides and it is known for its specific action against oomycetes.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Zoxamide may be used as a reference standard for the analysis of zoxamide in:
  • Grape, grape processing, and in the fermentation process by gas chromatography-ion-trap mass spectrometry (GC-ITMS) operating in electron ionization (EI) and chemical ionization (CI) modes.
  • Wine samples by liquid-liquid extraction (LLE)/clean-up and programmable temperature vaporization (PTV) injection in conjunction with GC-ITMS.
  • Wastewater samples by ultra-performance liquid chromatography-time-of-flight mass spectrometry (UPLC-TOF-MS).
  • Soya grains by LC with tandem mass spectrometry (MS/MS) in electrospray ionization (ESI) mode.
  • Food samples by UPLC-quadrupole MS/MS working under multiple reaction monitoring (MRM) mode.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation markEnvironment

Signal Word

Warning

Hazard Statements

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Skin Sens. 1A

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

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Molecular characterization of benzimidazole-resistant B. cinerea field isolates with reduced or enhanced sensitivity to zoxamide and diethofencarb.
Malandrakis A, et al.
Pesticide Biochemistry and Physiology, 99(1), 118-124 (2011)
Zhili Pang et al.
PloS one, 8(2), e56513-e56513 (2013-02-23)
Pyrimorph is a novel fungicide with high activity against the plant pathogen Phytophthora capsici. We investigated the risk that P. capsici can develop resistance to pyrimorph. The baseline sensitivities of 226 P. capsici isolates, tested by mycelial growth inhibition, showed
Post-harvest applications of zoxamide and phosphite for control of potato tuber rots caused by oomycetes at harvest.
Miller JS, et al.
American Journal of Potato Research, 83(3), 269-278 (2006)
Gas chromatographic ion trap mass spectrometry determination of zoxamide residues in grape, grape processing, and in the fermentation process
Angioni A, et al.
Journal of Chromatography A, 1097(1-2), 165-170 (2005)
Xujia Zhang et al.
Environmental toxicology and pharmacology, 78, 103405-103405 (2020-05-24)
Commercial benzamide fungicides are applied to crops to control damage caused by oomycete fungi and are used as veterinary pharmaceuticals in aquaculture. The mechanism of action of these fungicides is to induce mitotic arrest via binding to beta-tubulin, thus inhibiting

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