409510

Poly(ethylene glycol) dimethacrylate

average M_N 550, cross-linking reagent polymerization reactions, methacrylate, 80-120 ppm MEHQ as inhibitor, 270-330 ppm BHT as inhibitor

• Synonym(s): Polyethylene glycol, PEG dimethacrylate
• Linear Formula: C₃H₅C(O)(OCH₂CH₂)_nOC(O)C₃H₅
• CAS Number: 25852-47-5
• MDL number: MFCD00081877
• UNSPSC Code: 12162002
• PubChem Substance ID: 24865654
• NACRES: NA.23

Properties

• Product Name: Poly(ethylene glycol) dimethacrylate, average M_n 550, contains 80-120 ppm MEHQ as inhibitor, 270-330 ppm BHT as inhibitor
• form: liquid
• mol wt: average M_n 550
• contains: 270-330 ppm BHT as inhibitor; 80-120 ppm MEHQ as inhibitor
• reaction suitability: reagent type: cross-linking reagent; reaction type: Polymerization Reactions
• refractive index: n20/D 1.466
• bp: >200 °C/2 mmHg (lit.)
• density: 1.099 g/mL at 25 °C
• Ω-end: methacrylate
• α-end: methacrylate
• polymer architecture: shape: linear; functionality: homobifunctional
• storage temp.: 2-8°C
• SMILES string: OCCO.CC(=C)C(O)=O
• InChI: 1S/C10H14O4/c1-7(2)9(11)13-5-6-14-10(12)8(3)4/h1,3,5-6H2,2,4H3
• InChI key: STVZJERGLQHEKB-UHFFFAOYSA-N

Description

Application

• PDGF-AA loaded photo-crosslinked chitosan-based hydrogel for promoting wound healing.: This study investigates the use of a chitosan-based hydrogel, photo-crosslinked with Poly(ethylene glycol) dimethacrylate (PEGDMA), to deliver PDGF-AA and enhance wound healing. The results demonstrate significant improvements in wound closure rates and tissue regeneration (Cai et al., 2024).


• Reducing the foreign body response on human cochlear implants and their materials in vivo with photografted zwitterionic hydrogel coatings.: This research explores the application of PEGDMA in zwitterionic hydrogel coatings to minimize foreign body responses in cochlear implants. The coatings significantly reduced inflammation and improved biocompatibility in vivo (Horne et al., 2023).


• Full factorial design of experiment-based and response surface methodology approach for evaluating variation in uniaxial compressive mechanical properties, and biocompatibility of photocurable PEGDMA-based scaffolds.: This study uses a full factorial design to optimize the mechanical properties and biocompatibility of PEGDMA-based scaffolds, highlighting their potential use in tissue engineering and regenerative medicine (Bharadwaz et al., 2023).


• Antifouling and Mechanical Properties of Photografted Zwitterionic Hydrogel Thin-Film Coatings Depend on the Cross-Link Density.: This article examines how varying the cross-link density in PEGDMA-based hydrogel coatings affects their antifouling and mechanical properties. The findings are relevant for the development of durable and biocompatible medical device coatings (Jensen et al., 2021).


• Biocompatible and photocrosslinkable poly(ethylene glycol)/keratin biocomposite hydrogels.: The research presents the development of PEGDMA/keratin biocomposite hydrogels, demonstrating excellent biocompatibility and potential applications in drug delivery systems and tissue engineering (Wang et al., 2021).

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable