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Sigma-Aldrich

2-Ethyl-2-oxazoline

≥99%

Synonym(s):

2-Ethyl-4,5-dihydrooxazole, 2-Ethyloxazoline

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About This Item

Empirical Formula (Hill Notation):
C5H9NO
CAS Number:
10431-98-8
Molecular Weight:
99.13
EC Number:
233-912-4
MDL number:
MFCD00005302
UNSPSC Code:
12352100
PubChem Substance ID:
24848326
NACRES:
NA.22

Quality Level

100

Assay

≥99%

form

liquid

refractive index

n20/D 1.437 (lit.)

bp

128.4 °C (lit.)

mp

−62 °C (lit.)

density

0.982 g/mL at 25 °C (lit.)

SMILES string

CCC1=NCCO1

InChI

1S/C5H9NO/c1-2-5-6-3-4-7-5/h2-4H2,1H3

InChI key

NYEZZYQZRQDLEH-UHFFFAOYSA-N

General description

2-Ethyl-2-oxazoline undergoes cationic ring opening graft polymerization using tosylated cellulose nanowhisker as macroinitiator.

Application

2-Ethyl-2-oxazoline (EtOx) was used in synthesis of block copolymers of EtOx and styrene by cationic ring-opening polymerization and atom transfer radical polymerization.

Pictograms

FlameExclamation mark
GHS02,GHS07

Signal Word

Warning

Hazard Statements

H226,H302 + H312 + H332

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Flam. Liq. 3

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

84.2 °F - closed cup

Flash Point(C)

29 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Luqiao Wen et al.
Drug development and industrial pharmacy, 46(2), 283-295 (2020-01-17)
In this study, we evaluated and screened the effects of the molecular weight (MW) and molar ratio of poly(2-ethyl-2-oxazoline)-cholesteryl methyl carbonate (PEtOz-CHMC) on the pH sensitivity, stability, and antitumor efficacy of liposomes. The pH sensitivity of PEtOz-CHMC with different MWs
Shabnam Sattari et al.
International journal of biological macromolecules, 156, 1126-1134 (2019-11-22)
Although many techniques have been devoted to promote therapeutic purposes of drug carrier systems, however, there are still many challenges in this area. Here, we designed co-loaded delivery systems, composed of curcumin loaded cyclodextrin-graphene oxide core (Cur@CD-GO) and gallic acid
Ziqi Wang et al.
Acta biomaterialia, 62, 144-156 (2017-08-27)
To concurrently suppress multidrug resistance (MDR) and metastasis of breast cancer cells, paclitaxel (PTX) and honokiol (HNK) were coencapsulated into pH-sensitive polymeric micelles based on poly(2-ethyl-2-oxazoline)-poly(d,l-lactide) (PEOz-PLA). The physicochemical properties of dual drug-loaded PEOz-PLA micelles were characterized in size, drug
Abbas Dadkhah Tehrani et al.
Carbohydrate polymers, 97(1), 98-104 (2013-06-19)
The cellulose nanocrystals, prepared by acid hydrolysis of cotton linter, consisted of slender rods with an average length of 173 nm and diameter of 80 nm, respectively. The surface of obtained cellulose nanocrystals was chemically modified using tosyl chloride and
A Sofia Silva et al.
International journal of pharmaceutics, 519(1-2), 240-249 (2017-01-24)
Functionalized gold nanoparticles (AuNPs) have been widely investigated as promising multifunctional nanosystems for the theragnosis of lung cancer, the most common and prominent cause of cancer death worldwide. Nevertheless, nanoparticles are not in appropriate sizes for an accurate deep lung
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