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Key Documents

SRP0361

Sigma-Aldrich

PLK3 Polo Box Domain human

recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

Synonym(s):

CNK, FNK, PRK, polo-like kinase 3

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About This Item

UNSPSC Code:
12352200
NACRES:
NA.32

biological source

human

recombinant

expressed in E. coli

Assay

≥90% (SDS-PAGE)

form

aqueous solution

mol wt

80.5 kDa

packaging

pkg of 100 μg

NCBI accession no.

NM_004073
NP_004064

UniProt accession no.

Q9H4B4

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... PLK3(1263)

General description

Human N-terminal MBP tagged Plk3 polo box domain (GenBank Accession No.NM_004073/NP_004064), amino acids 335-646 with C-terminal His-tag, MW=80.5 kDa, expressed in an E. coli expression system.

Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Danger

Hazard Statements

H315,H319,H360D

Hazard Classifications

Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Zhongkui Li et al.
The Journal of biological chemistry, 280(17), 16843-16850 (2005-01-27)
RelA, the p65 subunit of NF-kappaB transcription factors, plays a key role in regulation of antiapoptotic and proapoptotic responses. However, the downstream target genes regulated by RelA-NF-kappaB in the initiation of proapoptotic signaling were not identified. We previously showed that
Suqing Xie et al.
Oncogene, 23(21), 3822-3829 (2004-03-17)
MEK1, a gene product that regulates cell growth and differentiation, also plays an important role in Golgi breakdown during the cell cycle. We have recently shown that polo-like kinase (Plk3) is Golgi localized and involved in Golgi dynamics during the

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