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SML3259

Sigma-Aldrich

Morroniside

≥95% (HPLC)

Synonym(s):

[1S-(1α,3β,4aβ,8β,8aβ)]-8-(β-D-Glucopyranosyloxy)-4,4a,8,8a-tetrahydro-3-hydroxy-1-methyl-1H,3H-Pyrano[3,4-c]pyran-5-carboxylic Acid Methyl Ester, b-Morroniside

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About This Item

Empirical Formula (Hill Notation):
C17H26O11
CAS Number:
25406-64-8
Molecular Weight:
406.38
MDL number:
MFCD00210532
UNSPSC Code:
12352200
NACRES:
NA.77
Pricing and availability is not currently available.

Quality Level

100

Assay

≥95% (HPLC)

form

powder

color

white to beige

storage temp.

-10 to -25°C

SMILES string

O1[C@H]([C@@H]([C@H]([C@@H]([C@H]1CO)O)O)O)O[C@@H]2OC=C([C@@H]3[C@H]2[C@@H](OC(C3)O)C)C(=O)OC

InChI key

YTZSBJLNMIQROD-KKORFXOPSA-N

Biochem/physiol Actions

Bioactive natural product with antioxidant and anti-inflammatory activity
Morroniside is a bioactive natural product with antioxidant and anti-inflammatory activity. Its activities have included protecttion against cerebral ischemia/reperfusion injury by inhibiting neuron apoptosis and MMP2/9 expression and regulation of hair growth and cycle transition via activation of the Wnt/β-catenin signaling pathway.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
0000329354
0000329354
0000201232
0000201231
0000161787

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Lijuan Zhou et al.
Scientific reports, 8(1), 13785-13785 (2018-09-15)
Hair loss is characterized by a shortened hair anagen phase and hair follicles (HF) miniaturization. Morroniside is the most abundant iridoid glycoside extracted from Cornus officinalis and has various bioactivities in different cell functions and tissue regeneration. In this study
Guoyong Zeng et al.
Experimental and therapeutic medicine, 16(3), 2229-2234 (2018-09-07)
The aim of the present study was to investigate the effect of morroniside against matrix metalloproteinase (MMP)2/9 and focal cerebral ischemia/reperfusion (I/R) injury in rats. A rat model of focal cerebral I/R injury rats was established and rats were administered
Kang Chen et al.
European journal of pharmacology, 834, 295-304 (2018-07-31)
Amyloid-β peptide (Aβ) plays a causal role in the development and progression of Alzheimer's disease (AD). Oxidative stress and activation of mitogen-activated protein kinase (MAPK) are involved in Aβ-induced neurotoxicity. Morroniside, one active monomer of dry ripe sarcocarp of Cornus

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