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500 μG
NOK 2,050.00
1 MG
NOK 3,070.00
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500 μG
NOK 2,050.00
1 MG
NOK 3,070.00
About This Item
Empirical Formula (Hill Notation):
C99H126N20O33S1
Molecular Weight:
2156.24
UNSPSC Code:
12352209
NACRES:
NA.32
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![[Leu15,Gly18]-Gastrin2-17](/deepweb/assets/sigmaaldrich/product/images/384/185/d3095ca6-fe9a-4e1c-b2e9-29ad2bd40c46/640/d3095ca6-fe9a-4e1c-b2e9-29ad2bd40c46.jpg)
Assay
≥95% (HPLC)
form
lyophilized
composition
Peptide Content, ≥68%
storage condition
protect from light
storage temp.
−20°C
Amino Acid Sequence
Glp-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-Gly
Application
Gastrin is a linear polypeptide that induces the secretion of gastric acid (HCl) by parietal cells. Gastrin is found in three major forms: gastrin-34 (big gastrin); gastrin-17 (little gastrin) and gastrin-13 minigastrin.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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J F Rehfeld
Acta physiologica (Oxford, England), 201(4), 405-411 (2011-03-12)
Gastrin and cholecystokinin (CCK) are homologous hormone systems known to regulate gastric acid secretion, gallbladder emptying, and cell growth in the pancreas and stomach. They are, however, also involved in the development and secretory functions of pancreatic islet cells. For
Mitchell L Schubert
Current opinion in gastroenterology, 27(6), 536-542 (2011-09-08)
The review summarizes the past year's literature regarding the regulation of gastric exocrine and endocrine secretion, both basic science and clinical. Gastric acid secretion is an elaborate and dynamic process that is regulated by neural (efferent and afferent), hormonal (e.g.
Sara Calatayud et al.
Mini reviews in medicinal chemistry, 10(1), 8-19 (2010-04-13)
Gastrin release is affected by gastric inflammatory conditions. Antral G cells respond to inflammatory mediators by increasing gastrin secretion. Accumulating experimental evidence suggests that gastrin exerts immunomodulatory and proinflammatory effects. Gastrin could be a contributing factor to these pathologies, which
Gastrin in gastrointestinal diseases.
Daniel Fourmy et al.
Gastroenterology, 141(3), 814-818 (2011-07-20)
Monica Cappellini et al.
Analytical methods : advancing methods and applications, 13(38), 4468-4477 (2021-09-09)
hPG80 (human circulating progastrin) is produced and released by cancer cells. We recently reported that hPG80 is detected in the blood of patients with cancers from different origins, suggesting its potential utility for cancer detection. To accurately measure hPG80 in
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