Anti-CD4 Antibody detects endogenous levels of total CD4 protein.
CD4 (CD4 molecule) is present in the surface of specific leukocytes. CD4 contains four ecto-domains (D1-D4) of which D1, D2, and D4 contain disulfide bonds. It is mapped to human chromosome 12p13.31.
Immunogen
The antiserum was produced against synthesized peptide derived from human CD4.
Immunogen Range: 401-450
Application
Anti-CD4, C-Terminal antibody has been used in immunohistochemical staining.
Biochem/physiol Actions
CD4 (CD4 molecule) helps in the activation of immunostimulatory T-cells. It serve as a primary receptor for HIV-1 entry.This molecule plays an important role on cell membrane mechanical characteristics and can be used in the development of cell biology and medicine.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Exogenous Lipocalin 2 Ameliorates Acute Rejection in a Mouse Model of Renal Transplantation
Ashraf MI, et al.
American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 16(3), 808-820 (2016)
Frontiers in immunology, 10, 2392-2392 (2019-11-05)
Background: Stroke patients with diabetes suffer from higher mortality rate and worsened neurological outcome. However, the responses of immune system to cerebral ischemia in the setting of diabetes remain poorly understood. Methods: In this study, we investigated the temporal profile
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 16(3), 808-820 (2015-11-26)
Lipocalin 2 (Lcn2) is rapidly produced by damaged nephron epithelia and is one of the most promising new markers of renal injury, delayed graft function and acute allograft rejection (AR); however, the functional importance of Lcn2 in renal transplantation is
The role of CD4 on mechanical properties of live cell membrane
Bui VC and Nguyen TH
Journal of Biomedical Materials Research Part A, 104(1), 239-244 (2016)
Human CD4 Metastability Is a Function of the Allosteric Disulfide Bond in Domain 2
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
