SIGLEC1, encoded by a immunoglobulin superfamily gene, is a lectin-like adhesion molecule which binds glycoconjugate ligands on cell surfaces in a sialic acid-dependent manner. It is a type I transmembrane protein expressed only by a subpopulation of macrophages and is involved in mediating cell-cell interactions. Alternative splicing of the gene produces a variant encoding a protein isoform that is soluble rather than membrane-bound; however, the full-length nature of this variant has not been determined.
Immunogen
SIGLEC1 (Q9BZZ2, 1616-1650) This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human SIGLEC1.
Physical form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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