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K3519

Sigma-Aldrich

KRM-III

≥98% (HPLC)

Synonym(s):

1,3-Dihydro-1,4-diphenyl-2H-imidazole-2-thione

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About This Item

Empirical Formula (Hill Notation):
C15H12N2S
CAS Number:
79220-94-3
Molecular Weight:
252.33
MDL number:
MFCD02712628
UNSPSC Code:
12352200
PubChem Substance ID:
329817137
NACRES:
NA.77

Assay

≥98% (HPLC)

form

powder

color

light yellow to light tan

solubility

DMSO: soluble ≥20 mg/mL

storage temp.

2-8°C

SMILES string

S=C1NC(=CN1c2ccccc2)c3ccccc3

InChI

1S/C15H12N2S/c18-15-16-14(12-7-3-1-4-8-12)11-17(15)13-9-5-2-6-10-13/h1-11H,(H,16,18)

InChI key

QKOAQVKXZJFMET-UHFFFAOYSA-N

Biochem/physiol Actions

KRM-III is an inhibitor of T cell antigen receptor (TCR), an inhibitor of phorbol myristate acetate (PMA) /ionomycin-induced nuclear factor of activated T cells (NFAT) activation and T cell proliferation.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H319

Hazard Classifications

Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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