This product is a further purification of product H3506 and may contain some residual salts, such as sodium chloride.
H3631
Hyaluronidase from bovine testes
Type VI-S, lyophilized powder, 3,000-15,000 units/mg solid
Synonym(s):
Hyaluronate 4-glycanohydrolase, Hyaluronoglucosaminidase
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3000 UNITS
NOK 1,610.00
15000 UNITS
NOK 5,370.00
30000 UNITS
NOK 9,650.00
NOK 1,610.00
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3000 UNITS
NOK 1,610.00
15000 UNITS
NOK 5,370.00
30000 UNITS
NOK 9,650.00
About This Item
CAS Number:
EC Number:
MDL number:
UNSPSC Code:
12352204
NACRES:
NA.54
NOK 1,610.00
Please contact Customer Service for Availability
Recommended Products
biological source
bovine testis
Quality Level
conjugate
conjugate (Glucosaminoglycan)
type
Type VI-S
form
lyophilized powder
specific activity
3,000-15,000 units/mg solid
mol wt
~55 kDa (four subunits of 14 kDa each)
relevant disease(s)
cancer
storage temp.
−20°C
Gene Information
cow ... HYAL1(515397) , HYAL2(281838)
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Biochem/physiol Actions
Hyaluronidase degrades hyaluronan and has been found to be inappropriately regulated during cancer progression.
These enzymes randomly cleave β-N-acetylhexosamine-[1→4] glycosidic bonds in hyaluronic acid, chondroitin, and chondroitin sulfates.
Unit Definition
One unit will degrade 0.75 μg of the polysaccharide hyaluronic acid per minute at pH 5.35 at 37 ºC (as measured by turbidimetric absorbance (λ: 600nm) when complexed with BSA after 45 minutes).
Preparation Note
Chromatographically purified
Other Notes
View more information on enzymes for complex carbohydrate analysis at www.sigma-aldrich.com/enzymeexplorer
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Resp. Sens. 1
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Articles
Explore the role of hyaluronan, hyaluronic acid structure, hyaluronan synthesis & degradation, and more. Find GAGs, hydrogels, and scaffold kits.
Uncover more about glycosaminoglycans and proteoglycans including the structure of glycosaminoglycans (GAGs), the different types of GAGs, and their functions.
Glycosaminoglycans are large linear polysaccharides constructed of repeating disaccharide units.
Protocols
To measure hyaluronidase activity, a turbidimetric determination assay is used at 600 nm. One unit of hyaluronidase activity will cause a change in absorbance of 0.330 per minute at pH 5.35 at 37 °C.
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We bought this product. H3631, Batch Number: SLCH2685. Could you please provide the info on componants like, what are other componants present along with Hyaluronidase which is 3909/mg of solid (40ug, what is the remaining 940ug)?
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