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EHU019021

Sigma-Aldrich

MISSION® esiRNA

targeting human TRIM63

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

description

Powered by Eupheria Biotech

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

TGAGCCAGAAGTTTGACACGTTGTATGCCATCCTGGATGAGAAGAAAAGTGAGTTGCTGCAGCGGATCACGCAGGAGCAGGAGAAAAAGCTTAGCTTCATCGAGGCCCTCATCCAGCAGTACCAGGAGCAGCTGGACAAGTCCACAAAGCTGGTGGAAACTGCCATCCAGTCCCTGGACGAGCCTGGGGGAGCCACCTTCCTCTTGACTGCCAAGCAACTCATCAAAAGCATTGTGGAAGCTTCCAAGGGCTGCCAGCTGGGGAAGACAGAGCAGGGCTTTGAGAACATGGACTTCTTTACTTTGGATTTAGAGCACATAGCAGACGCCCTGAGAGCCATTGACTTTGGGACAGATGAGGAAGAGGAAGAATTCATTGAAGAAGAAGATCAGGAAGAGGAAGAGTCCACAGAAGGGAAGGAAGA

Ensembl | human accession no.

ENSG00000158022

NCBI accession no.

NM_032588

shipped in

ambient

storage temp.

−20°C

Gene Information

human ... TRIM63(84676) , TRIM63(84676)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Yaohua Zhang et al.
Nature cell biology, 22(11), 1332-1345 (2020-10-28)
Dystrophin proteomic regulation in muscular dystrophies (MDs) remains unclear. We report that a long noncoding RNA (lncRNA), H19, associates with dystrophin and inhibits E3-ligase-dependent polyubiquitination at Lys 3584 (referred to as Ub-DMD) and its subsequent protein degradation. In-frame deletions in BMD

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